侵袭性肺部真菌感染103 例临床分析 - New Century Science Press.PDF

/index.php/gjph Global Journal of Public Health, 2016, Vol.3, No.2 Clinical analysis of 103 cases of invasive pulmonary fungal infection 1 2 Zu-ping Zhang , Zhi-ping Zeng 1Qixian peoples hospital of Shanxi Province, Qixian, Shanxi, China 2The 1st affiliated hospital of Gannan medical college respiratory medicine, Ganzhou, Jiangxi, China Received: Apr 05, 2016 Accepted: Apr 15, 2016 Published: Sep 26, 2016 DOI: 10.14725/gjph.v3n2a1485 URL: /10.14725/gjph.v3n2a1485 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Objective: To analyze the clinical features of invasive pulmonary fungal infection (IPFI), and to explore the prevention and treatment of IPFI. Methods: Clinical data of 103 cases with IPFI diagnosed in our hospital were retrospectively analyzed. Results: COPD, bronchial lung cancer, and the abuse of antibiotics were the main risk factors of IPFI, among which Candida albicans accounted for 57.3% and Aspergillus species accounted for 32%in all cases. The mortality of IPFI patients was 20.4%. Conclusions: IPFI is a secondary pulmonary infection because of variety of predisposing factors, and its mortality rate is high. Early diagnosing, effective treatment for the fungus and enhancing the nutrition are good for IPFI. Key words Invasive pulmonary fungal infection; Clinical analysis 侵袭性肺部真菌感染103 例临床分析 1 2 张祖平 ，曾治平 1 祁县地区人民医院，山西祁县，中国 2 赣南医学院第一附属医院呼吸内科，江西赣州，中国 通讯作者：张祖平 Email: zh-zuping@163.com 【摘要】目的 分析侵袭性肺部真菌感染（IPFI ）的临床特点，探讨防治对策。方法 对 103 例IPFI 的临床资料进行回顾性 分析。结果 IPFI 以 COPD 、支气管肺癌多见，滥用抗生素等是主要危险因素；念珠菌属占 57.3% ，其次为曲霉菌属占 32.0% ；病死率为20.4% 。结论 IPFI 是在多种诱发因素下继发的肺部感染，原发性 IPFI 少见；其病死率高，重视易患因素 的控制、尽早诊断，综合治疗可降低死亡率。 【关键