小肠移植中急性抗体介导排斥反应的病理学.PDF

® 2012 8 28 ; 20(24): 2310-2317 wcjd@ ISSN 1009-3079 (print) ISSN 2219-2859 (online) CLINICAL PRACTICE RESULTS: AMR lesions were widely distrib- uted in the allograft, involving muscular arter- , ies, arterioles, capillaries, vasa vasorum, venules and veins. The most serious AMR was observed in arterioles located in the submucosa and vasa vasorum. Main morphological changes included , fi brous necrosis of blood vessel wall, thrombo- sis, and leucocyte margination. Neutrophilic granulocyte infi ltration was noted in the edema- , , tous interstitium surrounding the involved blood vessels, with numerous erythrocytes ex- . travasated. The fibrocollagenous network and part of the smooth muscle cells of the outer layer Histological alterations in of the muscularis externa showed fi brous necro- transplanted small bowel sis. Foci of lysis were present in the outer layer after acute a