名解(2)（Famous solution (2)）.doc

名解(2)（Famous solution (2)） 1.HBsAg: HBsAg, the antigen component of the envelope of hepatitis B virus, encoded by the S gene. It can be synthesized in large amounts in infected liver cells and released into the bloodstream or other body fluids. Positive HBsAg indicates the presence of HBV infection. 2. chronic HBsAg carriers: serum HBsAg remained positive for more than 6 months; there was no obvious clinical symptoms and normal liver function; the main source of hepatitis B infection. 3. Dane particle Dane: that is, complete HBV particles. Of the genus DNA. It is divided into two parts: envelope and core. The envelope contains HBsAg, and the core contains ring double stranded DNA, DNA polymerase, core antigen and E antigen. 4.HBV DNA: hepatitis B virus nucleic acid, located at the core of HBV. There are 2 types: free HBV DNA almost simultaneously with HBeAg appear in the blood, is a specific and direct index of HBV infection (replication, infectious); integrated HBV DNA in chronic HBV infection, integrated into liver cell genome can lead to hepatitis B recurrence or canceration. It is the index of antiviral treatment of hepatitis B. 5. window period: self limiting HBV infection, serum anti HBc 3 ~ 5 weeks on the coming of the HBsAg, then the anti HBs has not yet appeared, HBsAg has disappeared, only the detection of anti HBc and anti HBe, this stage is called the window period. 6. acquired immunodeficiency syndrome, acquired, immune, deficiency, syndrome: aids. Refers to the pathogenicity of HIV caused by chronic infectious diseases, mainly through sexual contact and blood borne virus mainly invade and destroy CD4+ lymphocytes, impaired cellular immune function, finally complicated with various kinds of serious opportunistic infections and tumors. 7.HAART: Chinese American scientist David Ho in Vancouver in 1996 Tenth International AIDS conference issued a mixed drug treatment called cocktail, known as highly active antiretroviral therapy (highly active anti-retrovi