提高中药口服液澄明度方法的探讨（Discussion on improving the clarity of oral liquid of Chinese Medicine）.docVIP

提高中药口服液澄明度方法的探讨（Discussion on improving the clarity of oral liquid of Chinese Medicine） Discussion on improving the clarity of oral liquid of Chinese Medicine Update Date: 2009-09-25 Click: Liu Huiqing, Hubei College of Traditional Chinese Medicine, Shi Keli Keyword: Chinese herbal oral liquid to improve clarity Traditional Chinese medicine oral liquid has the advantages of easy taking, easy absorption, long storage and easy deterioration. However, most of the oral preparations of Chinese medicine are easy to precipitate after being placed for a period of time, which seriously affects their clarity. In order to solve this problem, we have made some discussions, and it is reported as follows. 1 instruments and drugs IH-50 type automatic slide machine; DYY- III 4 stabilized electrophoresis - electrophoresis tank; 25 type viscometer; acidity juice; NaOH (AR) - pyridine acetic acid water bathing solution; Polygonum multiflorum. 2 experimental methods and results 2.1 oral liquid, why Radix Polygoni Multiflori decoction, such as water, after the concentration of each ml this product equivalent to raw materials 1G. Take the Polygonum oral liquid in the beaker, put in the IH-25 type projector, Tyndall phenomenon obviously, so it can be proved that the oral liquid is a colloidal solution. Test and proof of 2.2 isoelectric point According to the large molecular solution in the isoelectric point, the viscosity should be the minimum principle, by Ubbelohde viscometer method, measuring the different pH value of the viscosity, the operation is as follows: take 40ml oral liquid, measured the initial pH value is 5.2, with a 0.1% NaOH solution to adjust the pH value, viscosity measurement table 1 by Ubbelohde viscometer. Table 1 The pH values are 6.60, 6.73, 6.80, 7, 7.20, 7.40 T, 49.5, 45, 43.5, 44.7, 46, 46.6 Using micro injector 50ml oral liquid on filter paper, with pyridine: acetic acid: water =25: 1: 274 for electrophoretic solution using DYY stabilized electrophoresis in 500