139例肛周尖锐湿疣临床特征及治疗观察.docVIP

139例肛周尖锐湿疣临床特征及治疗观察【摘 要】 目的:总结肛周尖锐湿疣的临床特征及二氧化碳激光治疗效果。方法：观察并总结2008年12月~2010年3月门诊治疗的139例肛周尖锐湿疣临床特征，对其在局麻下行二氧化碳激光治疗，并进行末次治疗后6个月的随访。结果：肛周尖锐湿疣主要见于19~45岁中青年，肛周尖锐湿疣患者中46.8%经常到洗浴中心洗浴。经典型菜花状皮损占肛周尖锐湿疣发病的70.5%，激光治疗随访超过3个月仅7例仍有新发皮疹。再经治疗，所有患者均获得临床治愈并且未见长期的副作用。结论：肛周各型尖锐湿疣的传染途径中公共洗浴中心的卫生状况是重要的原因之一。二氧化碳激光治疗肛周尖锐湿疣疗效高，不良反应少。 【关键词】 肛周； 尖锐湿疣（CA）； 临床特征； 观察 Clinical characteristics and therapy for 139 cases of perianal condylomata acuminate YANG Xifang, ZHANG Ronglin, ZHNAG Xiaohua, XU Nan, ZHOU Yanan, CHEN Qinfang, CAO Ningxiao Hospital of Dermatology, Chinese Academy of Medical Sciences, Jiangsu 210042, China 【Abstract】 Objectives: To observe the clinical characteristics of perinanal condylomata acuminate (CA) and the therapeutic effect of CO?2 laser treatment. Methods: The clinical characteristics and CO?2 laser therapeutic effects were observed for a total of 139 cases with perianal CA who had their outpatient visit to our hospital from December, 2008 to March, 2010. A follow-up study was also made six months after the last treatment. Results: Perianal CA were mostly common in the age group of 19-45 and a large percent (46.8%) of patients were found to frequently visit the bathing center. The classic cauliflower skin lesion accounted for 70.5% of CA occurrence. Only 7 cases revealed new skin irritation in three-month follow-up after laser treatment. They were then again treated with laser and showed complete recovery and no long-term side effects. Conclusion: Public bathing center might be the main transimission pathway for perianal CA. CO?2 laser treatment showed satisfactory therapeutic effects but little adverse effects. 【Key words】 perianal; CA; clinical characteristics; observation 尖锐湿疣（CA）是临床上常见的由人类乳头瘤病毒感染的性传播疾病。在我国发病率逐年增高，近10年来肛周CA的发病也迅猛增加，据报道肛周受累者超过患者总数的1/4[1]。现将我科门诊近期治疗的肛周各型CA病例报告如下。 1 临床资料和方法 1.1 病例来源2008年12月~2010年3月本科门诊共治疗肛周CA 139例。 CA诊断依据临床表现和醋酸白试验，必要时行病理活检，排除鲍温样丘疹病、二期梅毒疹等与CA难鉴别的皮肤病。按皮损的外形特点对其进行分型。所有患者中11例曾接受过包括电灼、冷冻、局部外用药物等肛周治疗。 1.2 治疗方法治疗时患