比索洛尔及美托洛尔对甲亢性心动过速疗效评价.docVIP

比索洛尔及美托洛尔对甲亢性心动过速疗效评价【摘要】 目的:观察比索洛尔和美托洛尔对治疗甲亢性心动过速的疗效。方法:将确诊为甲亢性心动过速90例患者分为两组,比索洛尔组和美托洛尔组,比索洛尔组55例,观察患者在其治疗4周后的心率变化,同时随机抽取其中30例患者,观察患者在其治疗1周后的心率变化;美托洛尔组35例,观察患者在其治疗4周后的心率变化,同时随机抽取其中21例患者,观察患者在其治疗1周后的心率变化,两组药物均在甲状腺基础用药上应用。最后评定两组在1周和4周后的疗效。结果:比索洛尔组和美托洛尔组在1周和4周后对控制甲亢性心动过速的显效率和总有效率无统计学差异,(P0.05)。结论:比索洛尔和美托洛尔对甲亢性心动过速的疗效相当。 【关键词】甲亢性心动过速;比索洛尔;美托洛尔 Bisoprolol and metoprolol on the efficacy evaluation of hyperthyroid tachycardia Fengcai Lian Jiang NingYi Sun Yunfeng Shi LiHong Jiang Song 【Abstract】 Objective: To observe the effect of bisoprolol and metoprolol on the efficacy of treatment of hyperthyroid tachycardia. Methods: The diagnosis of thyrotoxic tachycardia 90 cases were divided into two groups, bisoprolol group and metoprolol group, bisoprolol group of 55 cases observed in patients in their treatment for 4 weeks after the heart rate changes, while random sampling in which 30 patients were observed in patients treated 1 week after their heart rate changes; metoprolol group of 35 cases were observed in patients in their treatment for 4 weeks after the heart rate changes, while 21 patients were randomly selected in which to observe the patients in their treatment of 1 week after the heart rate changes, the basis of two groups of drugs are in the thyroid medication to apply. Final assessment of the two groups at 1 week and 4 weeks after the effect. Results: The effect of bisoprolol group and metoprolol group at 1 week and 4 weeks after control of hyperthyroid tachycardia significant efficiency and total efficiency is not statistically significant difference, (P 0.05). Conclusion: The effect of bisoprolol and metoprolol on the efficacy of hyperthyroid tachycardia fairly. 【Key words】 Thyrotoxic tachycardia ;bisoprolol;metoprolol 【中图分类号】R762【文献标识码】A【文章编号】1005-0515(2010)010-0021-02 甲状腺功能亢进(简称甲亢)是由于甲状腺或甲状腺以外的多种原因引起的甲状腺激素增多,进入循环血中,作用于全身的组织和器官,造成机体的神经,循环,消化等系统的兴奋性增高和代谢亢进为表现的疾病。而甲亢对机体心血管系统影响十分突出,据资料显示[1],甲亢患者心动过速的发生率约达82%,查体时,甲亢患者大陪分会出现心动过速的体征.。由于心动过速,导致心排出量