椎体成形术治疗骨质疏松性椎体骨折的随机安慰剂对照研究( 两年随访 .PDFVIP

ORIGINAL ARTICLE JBMR ( 椎体成形术治疗骨质疏松性椎体骨折的随机安慰剂对照研究 两 年随访结果) Two-Year Results of a Randomized Placebo-Controlled Trial of Vertebroplasty for Acute Osteoporotic Vertebral Fractures 1,2 1,3 4 5 6 7 Féline Kroon, Margaret Staples, Peter R Ebeling, John D Wark, Richard H Osborne, Peter J Mitchell, Chris HR 8 1,3 Wriedt, and Rachelle Buchbinder 1Monash Department of Clinical Epidemiology, Cabrini Institute, Victoria, Australia 2Department of Rheumatology, Leiden University Medical Centre, Leiden, the Netherlands 3Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Victoria, Australia 4NorthWest Academic Centre, University of Melbourne, Western Health, Victoria, Australia 5University of Melbourne Department of Medicine, and Bone and Mineral Medicine, Royal Melbourne Hospital, Victoria, Australia 6Public Health Innovation, Population Health Strategic Research Centre, Deakin University, Victoria, Australia 7University of Melbourne, Department of Radiology, Royal Melbourne Hospital, Victoria, Australia 8I-Med Network, Victoria, Australia 摘要 6 我们曾报道过 个月的随机临床对照研究，对于新鲜的骨质疏松椎体骨折，椎体成形和假手术无差异。本研究报道了 12 24 78 (38 ) (40 ) 个月及 个月的对照研究结果。 例患者入组，随机分成椎体成形术组 例和假手术组 例 。随机分类因素包 (6 6 ) ( ) 括治疗中心、性别以及症状 周或≥ 周 。参与者、研究者放射医师除外 ，以及结果评定者都被实施盲法。注册登 2004 4 2008 10 2010 10 0 10 记时间为 年 月到 年 月，随访到 年 月。主要指标是疼痛评分， 分为无痛， 分为最痛。其他指标 ( ) 12