复方地龙胶囊治疗中风(脑梗死)恢复期疗效及安全性.doc

复方地龙胶囊治疗中风(脑梗死)恢复期疗效及安全性[摘要] 目的 观察复方地龙胶囊治疗中风恢复期的疗效及安全性。方法 随机将80例中风患者分为治疗组48例、对照组32例；治疗组采用复方地龙胶囊，对照组采用脑安胶囊。结果 复方地龙胶囊总进步率75%，总有效率79.17%；脑安胶囊总进步率46.88%，总有效率46.88%，两组比较有统计学意义（P＜0.05）。结论 复方地龙胶囊具有化瘀通络、益气活血的功效，用于中风恢复期治疗能明显地改善患者的临床症状和体征，是中风恢复期治疗的有效药物。 [关键词]复方地龙胶囊 ； 中风恢复期 ；气虚血瘀 [中图分类号] R743.3 [文献标识码] B [文章编号]1673-9701（2011）22-118-02 Observation on the Efficacy and Safety of Stroke Recovery Period in the Treatment of Compound Earthworm Capsule WANG Lanjun LI Guoxing Medicine Laboratory， the First Affiliated Hospital of Xinxiang Medical College ，Weihui 453100 ， China [Abstract] Objective To observe the efficacy and safety of compound Earthworm capsule to to stroke recovery period. Methods Eighty patients at stroke recovery period were divided into two groups. Treatment group of compound Earthworm capsule was 48 cases and contrast group of Brain peaceful capsule was 32 cases. Results Total progress rate of compound Earthworm capsule groups was 75% and total effective rate was 79.17% .Total progress rate of Brain peaceful capsule groups was 46.88% and total effective rate was 46.88%（P ＜0.05 ）. Conclusion compound Earthworm capsule had effect of absorbing clots and activating cannals supplementing qi and activating blood cirulation，Ir could evidently better patients， clinical symotom and hysical sign.It wad a effective medicine to stroke recovery period . [Key words] Compound Earthworm capsule； Stroke recovery period； Deficiency of qi and blood stasis 复方地龙胶囊是由地龙、川芎、黄芪和牛膝等组成的纯中药制剂，具有化瘀通络、益气活血的功效，适宜中风病气虚血瘀证的治疗。2009年12月~2010年８月，我们应用复方地龙胶囊治疗中风（脑梗死）恢复期患者取得较好疗效，现报道如下。 1 资料与方法 1.1 一般资料 病例选择参照1995年中华医学会第四次全国脑血管病学术会议修订的《各类脑血管疾病诊断要点》纳入标准[1]，符合动脉粥样硬化血栓性脑梗死，符合中医辨证属中风病中经络恢复期气虚血瘀型辨证标准，年龄40～75岁，神经功能缺损程度积分＞６分且＜23分的轻、中型患者。 共入组80例，按随机数字表根椐入组顺序分为两组：治疗组48例，其中男30例，女18例，平均年龄（60.6±8.8）岁，平均病程（8.39±6.25）个月，NIHSS评分（10.313±2.561）；对照组32例，男18例，女14例，平均年龄（59.12±10.59）岁，平均病程（9.06±7.16）个月，NIHSS评分（10.063±2.380）。两组患者在年龄、身高、性别、病程、合并疾病、NIHSS评分和各单项指标、患者总的生活能力、日常生活自理能力、中医症状分析等方面比较，无