多囊卵巢综合征患者体重指数及脂蛋白代谢相关性分析.doc

多囊卵巢综合征患者体重指数及脂蛋白代谢相关性分析[摘要] 目的：探讨多囊卵巢综合征（PCOS）患者不同的体重指数与脂质代谢的相关性。方法：收集门诊患者病历资料，按照PCOS诊断标准及体重指数（BMI）分为正常对照组30例、PCOS患者非肥胖组（non-fat group）39例与PCOS患者肥胖组（fat group）31例。三组分别检测空腹高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）及三酰甘油（TG）血清值。结果：HDL-C在3组的血清值分别为（1.53±0.23）、（1.47±0.41）、（1.22±0.20）mmol/L。经统计学分析对照组与PCOS非肥胖组血清比较，差异无统计学意义（P=0.572）；PCOS肥胖组HDL-C值高于对照组及非肥胖组血清值（P=0.004、0.008）；PCOS肥胖组与非肥胖组在LDL-C与TG血清值上比较，两组间差异均无统计学意义（P=0.637、0.588）。结论：HDL-C血清水平可能与PCOS的病情程度有相关性。 [关键词] 多囊卵巢综合征；体重指数；高密度脂蛋白胆固醇；相关性 [中图分类号] R711.75 [文献标识码] B [文章编号] 1673-7210（2011）12（b）-178-02 Correlation analysis about lipoprotein serum level in different BMI patients of polycystic ovary syndrome ZHANG Chunhua Reproductive Health Center of Qianjiang District, Chongqing 409000, China [Abstract] Objective: To explore the correlation between polycystic ovarian syndrome (PCOS) patients′different body mass index and lipid metabolism of relevancy. Methods: Service medical records from outpatient were collected and divided into control group (30 cases), PCOS patients of non-fat group (39 cases) and PCOS patients of fat group (31 cases) in accordance with PCOS diagnostic criteria and body mass index (BMI). High-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) serum values were tested in three groups in fasting plasma. Results: Serum levels of HDL-C in three groups were (1.53±0.23), (1.47±0.41), (1.22±0.20)mmol/L; by statistical analysis, there was no statistically significant difference between PCOS patients of non-fat group and control group (P=0.572); serum levels of HDL-C in PCOS patients of fat group were more that in the control group and PCOS patients of non-fat group (P=0.004, 0.008); serum levels of LDL-C and TG between PCOS patients of non-fat group and PCOS patients of fat group were no obvious difference (P=0.637, 0.588). Conclusion: The serum levels of HDL-C may be having a correlation with PCOS illness extent. [Key words] Polycystic ovary s