我院2008年急诊不合理用药处方研究.doc

我院2008年急诊不合理用药处方研究[摘要] 目的:通过对不合理的处方进行调查分析,促进和提高合理用药水平。方法:随机抽取我院门诊34 282张急诊处方,根据药品的说明书、临床药理学知识,对不合理用药处方进行分析。结果:本组处方不合理率为4.20%,不合理用药主要反映在给药方案、重复用药、剂量、溶媒、用法、药理拮抗、配伍、毒性相加及禁忌证用药等方面。结论:医院门诊不同程度地存在不合理用药现象,应积极开展合理用药宣传,大力倡导和支持临床药师深入临床,与医师一道努力促进合理用药。 [关键词] 不合理用药;处方;分析 [中图分类号]R969.3 [文献标识码] C[文章编号] 1673-7210(2009)08(a)-189-03 Analysis of our hospital emergency unreasonable in 2008 prescription drug ZENG Wenyi, CHEN Li (Department of Pharmacy, Dongguan People’s Hospital, Dongguan 523018, China) [Abstract] Objective: To investigate the prescription unreasonable analysis, promote and improve the level of rational drug use. Methods: 34 282 emergency prescriptions were randomly sampled in our hospital, accorded to the manual medicine, clinical pharmacology expertise, to an analysis of prescription drug unreasonable. Results: The unqualified rate of the outpatient prescriptions in this group was 0.87%, irrational drug use was mainly a reflection of irrational drug use in the administration of the program, repeated drug use, dosage, solvent, use of pharmacological antagonists, compatibility, toxicity and the sum of the areas of drug contraindication. Conclusion: There is the phenomenon of irrational drug use in our hospital outpatient in different extent, rational drug use should be actively carried out propaganda, and vigorously advocate and support the clinical depth of clinical pharmacists, and physicians work together to promote rational drug use. [Key words] Irrational drug use; Prescription; Analysis 随着医药科学的发展,药物品种不断增加,处方用药也日渐复杂。多药同用,不合理用药现象随之出现,因此药源性疾病常因不合理用药而发生。如何安全、有效、合理、经济地使用药物,使患者身心健康早日痊愈,是药学工作者所面临的重要课题。同时如何指导临床合理用药是医院药剂科面临的新课题。对2008 年我院门诊急诊不合理用药处方情况进行分析, 目的在于为临床合理用药提供参考, 真正使药物的应用达到安全、有效、经济的目的,具体如下: 1 资料与方法 1.1 一般资料 随机抽取2008 年我院门诊急诊处方34 282张,所抽查科室包括神经内科、心内科、内分泌科、普通外科、神经外科、骨科、妇产科、皮肤科、口腔科、儿科、眼科、耳鼻喉科、专家诊室,从中挑选出不合理用药处方进行归类、分析。 1.2 方法 根据《中国药典用药须知》2005 年版、《新编药物学(第15版)》、药品说明书等有关文献, 对不合理用药处方中的给药方案不合理、重复用药、用法用量不合理、溶媒选择不当、配伍不合理、药物禁忌证等方面进行统计和分析。