曲马多及哌替啶治疗剖宫产术中寒颤比较.docVIP

曲马多及哌替啶治疗剖宫产术中寒颤比较[摘要] 目的 探讨曲马多与哌替啶在治疗剖宫产术中寒颤的效果。方法 选择拟行剖宫产术、ASAⅠ～Ⅱ级、年龄20～35岁、体重54～86 kg、无心肺系统疾病的足月产妇80例，随机分成T组（曲马多组）与P组（哌替啶组），两组均行腰硬联合麻醉，取出胎儿后出现寒颤患者T组给予曲马多1 mg/kg于莫非氏管滴入，P组给予哌替啶1 mg/kg于莫非氏管滴入，观察记录寒颤停止的时间、治疗寒颤的效果与患者BP、HR、RR、SPO2的变化以及药物不良反应。结果 在用药后寒颤消失患者分别为T组37例（92.5%），P组38例（95%），两组比较无统计学意义，BP、HR、RR两组比较差异无统计学意义（P ＞ 0.05），但P组的起效时间（8.5±2.5） min较T组（3.8±0.95） min缓慢，P组中SPO2有8例低于95%，T组无SPO2下降，两组比较差异有统计学意义（P ＜ 0.05）。两组的不良反应差异无统计学意义（P ＞ 0.05）。 结论 静脉注射曲马多与哌替啶均能有效抑制剖宫产术中的寒颤反应，但曲马多起效时间快，呼吸抑制少，更适于治疗剖宫产术中的寒颤反应。 [关键词] 曲马多；哌替啶；剖宫产；寒颤 [中图分类号] R614 [文献标识码] B [文章编号] 1673-9701（2012）03-0154-02 Tramadol and pethidine in the treatment of shivering more cesarean section ZHU Weijian WU Xiaomei LIU Qian Department of Anesthesiology, Guangdong Province Zhuhai City Xiangzhou District Nanping Hospital, Zhuhai 519060, China [Abstract] Objective To investigate the Tramadol and pethidine in the treatment of shivering effect of cesarean section. Methods Proposed cesarean section, ASAⅠ-Ⅱ， aged 20-35 years old, weighing 54-86 kg, no full-term maternal heart and lung diseases, 80 cases were randomly divided into group T(tramadol group) and the P group(pethidine group), two groups underwent epidural anesthesia, to remove the baby after the chills of group T patients given tramadol could venturi infusion at 1 mg/kg, P group was given pethidine 1 mg/kg on could venturi infusion, observed and recorded the time to stop shivering, shivering effect of treatment, patients with BP, HR, RR, SPO2 changes and adverse drug reactions. Results In the disappearance of shivering in patients after treatment the two groups were T group, 37 cases(92.5%), P group， 38 patients(95%)， showed no significant difference, BP, HR, RR showed no significant difference (P ＞ 0.05)， but the onset time of P group (8.5 ± 2.5) min than the T group (3.8 ± 0.95) min slow, P group, 8 patients SPO2 less than 95%, T was no SPO2 decreased, the two groups there was a significant difference (P ＜ 0.05). The two groups no signifi