资源县368例儿童手足口病流行病学特征研究.docVIP

资源县368例儿童手足口病流行病学特征研究摘要: 目的:对资源县2008年5月1日至2009年3月31日发病的儿童手足口病的临床流 行病学特征进行分析,为防治该病提供理论依据。方法:对368例收治住院病例进行 临床流行病学分析。结果:发病年龄以6岁以下(91%以上)多见,男性 患儿多于女性,发病高峰为5～8月份,52.7%患儿发病前有流行病学接触史,临床表现典型 ,症状轻微,少数患儿并发脑膜脑炎、心肌损害、肺炎和肝功能损害,有9例重症,死亡1例 。结论:手足口病只要早发现、早诊断、早隔离、早上报、早治疗,并给予足够的重视,患 儿大部分预后良好。 关键词:手足口病;流行病学;儿童 中图分类号: R512.5 文献标识码: A 文章编号: 1008-2409(2009)06-1007-03 Clinical epidemiological characteristics of hand-foot-mouth disease in 368 children in Ziyuan county/ZHANG Cai-ru, FANG Xiu-luo, LI He-wei,et al. ∥The Peoples Hospital of Ziyuan, Guilin 541400, China Abstract: Objective: To analyze the epidemiological and clinical characteristics of childr en with hand-foot-mouth disease(HFMD) in Ziyuan county area from May. in 2008to Mar. in2009, in order to prevent and treat diseases in the region andprovide a theor etical basis. Methods: 368 inpatients from May. in 2008 to Mar. in 2009 were in vestigated for epidemiological information and clinical features. Results: 368 c h ildren were hospitalized. The prevalent peak was from May to Aug. Most (91%)of the HFMD children were 6 or below 6 years old. Most cases (52.7%) had a his tory of contacting with HFMD cases before on set of the disease. The clinical manifestations of inpatients who had fever, ora l ulcers and vesicular rash appearing on the hands, feet, knees, and/or buttockswere typical and mild. The clinical complications occurred in some patients, in cluding encephalitis or aseptic meningitis, myocardial injury, pneumonia and liv er function injury. There were 9 severe and 1 fatal cases. Conclusions: The HFMDcan be healed and prevented.The prognosis of HFMD was good if the disease coul d be early discovered, diagnosed and managed. Key words:hand-foot-mouth disease; epidemiology; children 手足口病(Hand foot and mouth disease, HFMD)是由肠道病毒引起的儿童常见的急性 传染病,多发生于5岁以下儿童,可引起手、足、口腔等部位的疱疹,少数患儿可引起心肌 炎、肺水肿、无菌性脑膜脑炎等并发症,个别重症患儿如果病情发展快可导致死亡。引发手 足口病的肠道病毒有20多型,柯萨奇病毒A组的16、4、5、9、10型,B组的2、5型,以及 肠道病毒71型均为手足口病较常见的病原体,其中以柯萨奇病毒A16型(Cox A16)和肠道病