超声内镜在胃癌术前分期检查中应用价值.docVIP

超声内镜在胃癌术前分期检查中应用价值[摘要] 目的：探讨超声胃镜在胃癌术前分期检查中的应用价值。方法：对78例胃癌患者行术前超声胃镜检查及TNM分期，与术后病理检查结果比较并计算准确率。结果：超声内镜对胃癌浸润深度检测与术后病理检查相符70例，准确率为89.7%，对胃癌淋巴结转移检测与术后病理检查相符59例，准确率为75.6%。结论：超声胃镜对胃癌的TNM分期有较大的临床应用价值。 [关键词] 超声胃镜；胃肿瘤；TNM分期 [中图分类号] R735.2 [文献标识码] B [文章编号] 1673-7210（2011）12（b）-168-02 Clinical study of endoscopic ultrasound in gastric cancer preparation staging YANG Chi1, HUANG Mei1, PENG Lidong1, DOU Liqiong1, HU Xiaozhen2 1.Department of Special Medical Service, the Four Hundred and Twenty-Two Hospital of PLA, Guangdong Province, Zhanjiang 524000, China；2.Department of Special Medical Service, the three hundred and three Hospital of PLA, Nanning，Guangxi Zhuang Autoumous Region, Nanning 530021, China [Abstract] Objective: To investigate the application of the endoscopic ultrasound (EUS) examination in the preoperative staging of gastric cancer. Methods: 78 patients with gastric cancer were assigned to preoperative EUS examination and TNM staging, which were compared with postoperative pathological examination results to calculate the accuracy. Results: Compared with pathological staging, 70 cases of T staging and 59 cases of N staging assigned to EUS were consistent, and the accuracy of which were 89.7% and 75.6%, respectively. Conclusion: The endoscopic ultrasound for TNM staging of gastric cancer is of greater clinical value. [Key words] Ultrasound gastroscopy; Gastric cancer; TNM staging 胃癌是临床常见的恶性肿瘤，目前仍采取以手术为主的综合治疗。肿瘤的TNM分期是采取何种手术方案的主要依据。超声内镜结合了内镜与超声检查的优势，可较好地判断肿瘤浸润深度及淋巴结转移情况[1]。本文回顾性分析了78例经超声内镜检查的胃癌患者的临床资料，探讨其在胃癌术前分期检查中的诊断价值。 1资料与方法 1.1 一般资料 78例经活检证实为胃癌的患者均行超声内镜检查，其中，男59例，女19例，年龄28~71岁，平均（55.6±8.3）岁。患者在行超声内镜检查1周后行胃癌根治术或姑息性手术治疗。按病变部位：贲门胃底11例，胃体13例，胃角16例，胃窦28例，弥漫浸润性10例。术后病理主要为腺癌，其中，低分化癌21例，印戒细胞癌9例。 1.2 方法 超声内镜为日本奥林巴斯公司生产UMIR型腔内微型超声探头，频率为7.5、12.0、20.0 MHz。检查前准备同胃镜，开始前15 min服二甲基硅油5 ml，用4%利多卡因对咽峡部位作喷雾麻醉，超声内镜进入胃腔后吸净胃内容物，在胃镜检查发现病灶的部位注入脱气水500~800 ml，立即行超声检查，对不易蓄水的部位采取变换体位的方法注水检查。扫描并记录病变范围及浸润深度，依次探查胰、脾及脾门淋巴结，左肝、肝门区淋巴结，胃网膜左、右淋巴结，胃左、右淋巴结，腹腔淋巴结，