老年血脂异常与冠状动脉狭窄程度的相关性研究.doc

韩华1 王志铭1 冉威1 王刚2 张健夫3 （1辽宁医学院附属第三医院放射科2辽宁辽宁医学院附属第一医院放射科 3 辽宁医学院 锦州 121000） ［摘要］目的 探讨多层螺旋CT评价老年血脂异常与冠状动脉狭窄程度的相关性。方法 选择300例60岁以上由于胸痛首次入院疑诊冠心病患者，其中未合并血脂异常患者77例作为对照组，合并血脂异常患者223例作为观察组，并依据血脂异常危险分层分为低危组、中危组、高危组。应用64层螺旋CT冠状动脉成像技术，采用Gensini积分评价冠状动脉病变程度，并计数冠状动脉病变的支数。采用单因素方差分析及Pearson相关性分析观察老年血脂异常与冠状动脉狭窄程度间的关系。结果 中危、高危与对照组狭窄程度评分及狭窄数量比较均高于对照组（P＜0.05）；低危组与对照组比较无明显差异（P＞0.05）。组间比较，除对照组与低危组外，其他各组间差异均具有统计学意义（P＜0.05）。结论 老年血脂TC、TG、LDL-C、HDL-C与冠状动脉狭窄支数、程度相关；老年血脂异常危险分层与冠状动脉狭窄支数、程度相关。 关键词：多层螺旋CT；血脂异常；冠状动脉疾病；冠脉CTA MSCT evaluated the correlation between dyslipidemia of elderly population and coronary artery stenosis HANHua1, WANGZhi-ming1,RANWei1,WANGGang2,ZHANGJian-fu3 (1.Department of radiology, the third Affiliated Hospital of Liaoning Medical University, China 2.the First Affiliated Hospital 3. Liaoning Medical University, Jinzhou 121001,China ) [Abstract]：Object Investigate the correlation between multislice spiral CT to evaluate dyslipidemia of elderly population and the degree ofcoronary artery stenosis. Method Select 300 cases over 60 years patients first in admitted to hospital since pain in the chest with suspected coronary artery disease, no dyslipidemia patients （n=77cases）as a control group,dyslipidemia patients （n=223cases）as the observation group，and based on risk stratification of dyslipidemia，divided them into low-risk group, middle-risk group, high-risk group. Application of 64-slice spiral CT coronary imaging technology,evaluated coronary artery lesions by the Gensini score and count the counts of coronary artery disease. Univariate analysis of variance and Pearson correlation analysis to observed the relationships of dyslipidemia in elderly patients and the degree of coronary artery stenosis. Result the degree of stenosis and the counts of coronary artery in middle-risk group and high-risk group are higher than control group（P＜0.05）,there is no different between low-risk group and control group（P＞0.05）．The comparison among groups are differences（P＜0.05）,ex