肺间质性疾病的HRCT 表现及相关病理研究 - 放射学实践.PDFVIP

2002 9 17 5 Radiol Practice, Sept 2002, Vol 17, No. 5 4 3 HRCT 张晓莹 张令羽 周怀琪 冯颖 蒋鹏 房斌 = :分析肺间质性疾病的HRCT 表现及其与病理学的关 : 38例经手术病理证实的肺间质纤维化 患者和疾病对照组14 例分别行HRCT 扫描组织病理学检查( 包括HEMasson 氏三色染色) 及免疫组化: 早期组 中肺小叶间隔增厚81.25% , 肺内渗出毛玻璃影18.75% , 肺内小结节影66.67% , 胸膜下曲线12.5% ; 中晚期组中肺小叶 间隔纡曲僵直变形85.71% , 支气管血管束纡曲僵直 35.71% , 范围较广的肺气肿32. 14% , 蜂窝肺28. 57% , 胸膜增厚 39.29% : HRCT 是一种安全反映准确无创性的诊断 ILD 的手段, 经与病理对照, 毛玻璃影小叶间隔增厚肺内 小结节影网状影和胸膜下曲线是ILD 早期征象; 而肺小叶间隔纡曲僵直变形,支气管血管束纡曲僵直, 范围较广的肺 气肿及蜂窝肺是中晚期的征象 = 肺间质性疾病 高分辨率CT 病理学 = R814. 42, R563. 1 3, R361 3 = A = 1000-0313( 2002) 05-0403-04 HRCT appearances and associated pathological study of interstitial lung diseases ZHANG Xiaoying, ZHANG Lingyu, ZHOU Huaiqi, et al. Department of Radiology,the First Affiliated Hospital of Lanzhou Medical College, Gansu 730000 = Abstract Objective: To analyze the HRCT appearances of interstitial lung diseases (ILD) .Methods:38 cases w ith patho- logically proved ILD and 14 cases of control group were performed HRCT scanning,histological and immunohistochemistry exam-i nations. Histological examinations included HE staining and Masson. s trichrome staining.Results:Early stage interstitial lung dis- eases had the follow ing HRCT findings: interlobular septal thickening ( 81. 25%) , ground glass opacity( 18. 75%) ,t iny nodular shadow(66.67%) , and subpleural curved lines( 12.5%) . On the other hand, median and late stage had the following HRCT find- ings:twisting,rigidity and irregularity of interlobular septa ( 85.71%) and bronchovascular bundles(35. 71%) , emphysema ( 32. 14%) , honeycombing ( 28. 57%) and pleural thickening ( 39. 29%) . Conclusion: HRCT is a safe, sensitive and non-invasive method in the diagnosis of ILD.T he HRCT features are well correlated with the pathological findings. = Key words Interstitial lung disease High resolution computed tomography Pathology