岩斜区脑膜瘤.pdfVIP

CLINICAL STUDIES Impact of Computed Tomographic and Magnetic Resonance Imaging Findings on Surgical Outcome in Petroclival Meningiomas Gustavo A. Carvalho, M.D., Cordula Matthies, M.D., Marcos Tatagiba, M.D., Rama Eghbal, M.D., Madjid Samii, M.D. Department of Neurosurgery (GAC, CM, RE, MS), Nordstadt Hospital, and Department of Neurosurgery (MT, MS), University Medical School, Hannover, Germany OBJECTIVE: The preoperative radiological findings of computed tomographic and magnetic resonance imaging scans of 70 patients with petroclival meningioma were evaluated and statistically compared with the degree of surgical resection and patients’ outcomes to depict the most important radiological findings that may influence surgi- cal radicality and outcome. METHODS: The following parameters were evaluated: 1) tumor diameters; 2) tumor extension toward the middle fossa, the internal auditory canal, the brainstem, and the foramen magnum; 3) bone changes; 4) peritumoral edema; 5) signs of tumor infiltrative pattern; and 6) surgical radicality. Postoperative results were analyzed immediately after the surgery and in a long-term follow-up study. RESULTS: Larger tumors affected a younger population and presented a significantly shorter time until symptom onset. In the majority of cases (67%), the tumor extended to the parasellar region. Tumor extension toward the jugular foramen was found in 24% of the patients and reached the level of the foramen magnum in 18%. Irregular tumor margins were found in 67% of the tumors, and 50% of them presented peritumoral edema in