外周血白细胞计数与冠心病_李利华.pdfVIP

大理学院学报 第10卷第2 期 2011年2 月 JOURNAL OF DALI UNIVERSITY Vol.10 No.2 Feb. 2011 外周血白细胞计数与冠心病 李利华，杨 瑛，董 榆，黄修献，吴新华 （大理学院附属医院，云南大理 671000） ［摘要］目的：研究外周血白细胞计数及其亚群与冠脉病变之间的关系。方法：收集本院2009年3月至2010年5月所有进行冠脉造 影患者的相关数据，并进行统计分析。结果：和冠脉造影正常者（n=20）相比，冠心病患者（n=52）外周血白细胞计数、中性粒细胞 计数、中性粒细胞比例、中性/淋巴细胞比例显著升高，淋巴细胞比例显著降低（P ≤0.03）。对冠脉病变范围与白细胞计数及其亚 群的分析发现，与冠脉无病变者相比，冠脉病变者外周血白细胞计数、中性粒细胞计数、中性粒细胞比例、中性/淋巴细胞比例显 著升高，淋巴细胞比例显著降低（P ≤0.02）。结论：外周血白细胞计数及分类可能有助于预测冠状动脉病变及其严重程度。 ［关键词］白细胞计数；冠脉造影；冠脉病变 ［中图分类号］R541.4 ［文献标志码］A ［文章编号］1672-2345 （2011）02-0030-03 Association between Peripheral Leucocyte Count and Coronary Heart Disease LI Lihua, YANG Ying, DONG Yu, HUANG Xiuxian, WU Xinhua （Affiliated Hospital of Dali University, Dali, Yunnan 671000 ，China） 〔Abstract 〕Objective: To investigate the relationship between peripheral leucocyte count and coronary atherosclerosis disease. Method: The data of 72 patients who received coronary angiography for the first time during March 2009 and May 2010 were collected and analyzed. Results: The peripheral leucocyte count, neutrophil count, neutrophil proportion, neutrophil/lymphocyte ratio were significantly higher in patients with angiographically abnormal coronary arteries group （n=52）compared with the patients with angiographically normal arteries group （n =20）（P ≤0.03）. However, the lymphocyte proportions were significantly lower in the angiographically abnormal group （P ≤0.02）. Conclusions: Peripheral leucocyte count and classification may predict the lesion and severity of coronary atherosclerosis. 〔Key words 〕leucocyte count; coronary artery angiography; coronary atherosclerosis 冠心病是一种多基因遗传病，基因、环境因素 心内科住院的冠心病患者72例，男58例，女