Biomineralization课件.pptVIP

Biomineralization;Lecture Outline;What is Biomineralization?;Definition;Examples;Examples;Many Functions;General Biomineralization Mechanism;Why do we care about calcification?;Why do we care about calcification?;Bone;Endochondral Ossification;Formation of long bones examples: humerus, radius, ulna, femur, tibia, fibula Mesenchymal cells migrate to site of bone formation Mesenchymal cells give rise to chondrocytes and form the shape of bone Chondrocytes secrete ECM Chondrocytes continue to grow until they become encapsulated in the ECM Primary ossification Mature chondrocytes hypertrophy Cart