药理学25（Pharmacology 25）.docVIP

药理学25（Pharmacology 25） Lesson 23 Teaching methods: (Please tick tick) theory class discussion class - Experiment - - - other exercises Class arrangement: 1 hours Subject of instruction (chapter, section, or topic): Chapter twenty-seventh diuretics and dehydrating agents Teaching aims and requirements (three levels of mastery, familiarity and understanding): 1. to understand the pharmacological effects and mechanisms of various diuretics. To master the clinical application and application principle of diuretics, major adverse reactions and medication precautions. 2. to understand the mechanism of the action of dehydrating drugs, and to familiarize themselves with its clinical use. Teaching emphases and difficulties: 1. physiological processes of urine production and the physiological basis of diuretic action. The relation between the thickness of the medulla in the ascending part of the 2. medullary loop and the dilution and concentration of urine. 3. the relationship between the action site and the action of the diuretic. Relationship between the site of action of 4. acting diuretic and its action. 5. low diuretics: spironolactone, triamterene, mechanism of action, clinical use of acetazolamide. 6. the effects of diuretics on the electrolytes such as Na+, Cl-, Ca2+, Mg2+, K+ and so on 7., the role of dehydration drugs, clinical use, contraindications. The relation between the thickening and condensing of the medulla and the cortex of the ascending branch of the 1. medullary loop. 2. the role, location and mechanism of high efficacy diuretics, middle effect diuretics and low efficiency diuretics. 3. the influence of diuretics on Na+, Cl-, Ca2+, Mg2+, K+ and other electrolytes. 4. medium acting diuretics: pharmacological actions, mechanisms, clinical uses, and adverse effects of thiazide. 5. inefficient diuretics: mechanism of spironolactone, amiloride, triamterene, acetazolamide. 6. the mechanism of action, clinical use and contraindications of dehydrating drugs. Bas