荧光原位杂交技术(fish)技术在疾病分型诊断中的应用（Application of fluorescence in situ hybridization (FISH) technique in diagnosis of disease classification）.docVIP

荧光原位杂交技术(fish)技术在疾病分型诊断中的应用（Application of fluorescence in situ hybridization (FISH) technique in diagnosis of disease classification） Application of fluorescence in situ hybridization (FISH) technique in diagnosis of disease classification With the development of life science and the progress of biotechnology, our understanding of the nature of disease continues to deepen, and we have more new therapies and drugs to deal with the threat of disease. How accurate and effective use of these new therapies and drugs to cure diseases is an urgent need for us to study. How to correctly classify and diagnose the disease is the basis of the above work. Only by comprehensively grasping the disease and making accurate judgment and Analysis on this basis can we formulate a timely and effective treatment plan for the patient. Therefore, we call for the diagnosis of disease to provide more accurate and timely results. And the old look, smell, ask, cut and traditional traditional methods are far from enough to meet our requirements for disease diagnosis. Therefore, it is urgent to introduce new technologies into the field of disease diagnosis. Florescence In-Situ Hybridization (FISH) is a technique for detecting in situ hybridization samples using non radioactive fluorescent signals. It will be of high sensitivity and safety of fluorescence signal, high accuracy of fluorescence signal directly and in situ hybridization combined with fluorescently labelled DNA probes were hybridized with the sample DNA, the identification and counting of the fluorescence signal under the fluorescence microscope, so as to carry out the detection and diagnosis of chromosome or gene abnormality cell and tissue samples, provide the basis for accurate classification, for a variety of gene related diseases and prognosis of pre. Since the end of 1980s, Pinkel and Heiles will FISH technology into the field of chromosome detection, FISH technology has been widely used in clinical diagnosis and research wor