布洛芬混合液直肠给药在治疗小儿高热惊厥中临床疗效探析.docVIP

布洛芬混合液直肠给药在治疗小儿高热惊厥中临床疗效探析四川省林业中心医院儿科，四川成都610081 【摘要】目的：探讨布洛芬混合液直肠给药治疗小儿高热惊厥的临床疗效。方法：回顾性分析我院74例高热惊厥患儿的临床资料，观察组37例患儿给予布洛芬混合液直肠给药治疗，对照组37例患儿给予肌内注射安痛定治疗，比较两组患者的临床疗效。结果：观察组37例患儿经治疗后，总有效率为97.3%，显著高于对照组的83.8%，组间差异有统计学意义（P0.05），两组患儿在治疗过程中均未出现严重的不良反应。结论：布洛芬混合液直肠给药治疗小儿高热惊厥临床疗效好，且不良反应发生率低，故可作为治疗小儿高热惊厥的首选方法。 【关键词】小儿高热惊厥；布洛芬混合液；直肠给药；疗效 【中图分类号】R720.597【文献标识码】A文章编号：1004-7484（2012）-05-0741-02 Clinical effect about rectal administration of Ibuprofen mixture liquid in the treatment of children with febrile convulsionCHEN Qun-ying 【Abstract】Objective：To investigate the clinical effect of ibuprofen mixture liquid in the treatment of children with febrile convulsion. Methods：Clinical data of 74 children with febrile seizures were analyzed retrospectively，37cases in observation group were given rectal administration of Ibuprofen mixture liquid，37 cases in control group were given intramuscular injection Antongding treatment，compared clinical effect of patients in two groups of.Results：In observation group，the total effective rate was 97.3%，significantly higher than the control group of 83.8%，the difference between tw groups was statistically significant (P0.05)，patients in the two groups had no severe adverse reaction.Conclusion：Rectal administration of Ibuprofen mixture liquid in the treatment of children with febrile convulsion has good clinical curative effect，and a low incidence of adverse reactions，it can be used as the preferred method in treatment of children with febrile convulsion. 【Key words】Children with febrile convulsion；Ibuprofen mixed liquid；Rectal administration；Effect高热惊厥是指是小儿较为常见的惊厥类型之一，及时的解痉和退热是治疗的关键，以往口服或静脉滴注等方式给药很难达到理想的治疗效果［1］，我院近年来采用布洛芬混合液直肠给药治疗小儿高热惊厥取得了较好的临床疗效，现将相关研究结果报道如下：1.资料与方法 1.1一般资料：所有患儿均为我院2007-2011年间收治的高热惊厥患儿，符合小儿高热惊厥的诊断标准。其中，观察组男性22例，女性15例，年龄9个月-6岁，平均年龄2.7岁，体温39.2℃-40.3℃，平均39.5℃，有明确感染灶和病因28例。对照组男性20例，女性17例，年龄7个月-7岁，平均年龄3.2岁，体温39.3℃-40.7℃，平均39.8℃，有明确感染灶和病因25例。两组患儿在性别、年龄、体温等方面差异未见统计学意义（P＞0.05），组间具有可比性。 1.2治疗方法：所有患儿入院后均给予吸氧、抗感染、抗惊厥、纠正水电解质紊乱等对