客观测量正常皮肤及紫外线照射后皮肤颜色变化.docVIP

客观测量正常皮肤及紫外线照射后皮肤颜色变化[摘要]目的：比较两种仪器Chromameter CM2500d 和Maxmeter MX18在客观测量正常皮肤颜色及紫外线照射后皮肤颜色时的异同。方法：Chromameter CM2500d 的输出结果为L*a*，Maxmeter MX18的输出结果为M和E。其中L*和M反映皮肤黑素的变化，而a*和E则反映皮肤红斑的变化。测量正常皮肤曝光和非曝光部位的皮肤颜色，比较两种仪器的异同；分别以最小红斑剂量（MED）、即时黑化量（IPD）和最小持续黑化量(MPPD)的紫外线照射皮肤及反复多次紫外线照射皮肤，比较两种仪器在测量不同形式紫外线照射后皮肤颜色变化的异同。结果：在测量正常皮肤颜色时，两种仪器的检测指标具有很好的相关性；当紫外线照射后，反映色素变化的指标L*比M更易受皮肤红斑的影响；在测量IPD和MPPD产生的色素以及色素变化规律时两者具有很好的相关性；a*与E作为反映红斑的指标，在测量MED诱导的红斑时两者有很好的相关性，但反复紫外线照射红斑产生过强时，两者的相关性却明显的下降。在记录红斑随时间的变化过程中，两者始终保持较好的相关性。结论:两种仪器在不同情况下测量皮肤颜色时相关性不同，要根据具体情况分析检测结果。 [关键词]客观测量；皮肤颜色；紫外线 [中图分类号]R334.5[文献标识码]A [文章编号]1008-6455（2008）07-1038-03 Physical measurement and evaluation for the skin color of normal and UV-irradiated skin --Comparing study of Chromameter CM 2500d and Maxmeter MX18 TIAN Yan,LIU Wei,XIN Xu-ya,ZHANG Ping (Department of Dermatology,the General Hospital of Air Force,Beijing,100036,China) Abstract:ObjectiveTo compare the correlation of two kinds of instrument-- Chromameter CM2500d and Maxmeter MX18-in skin color measurement of normal and UV irradiated skin. Methods The result of Chromameter CM2500d is showed as L*a* and Maxmeter MX18 is M and E value. L* and M represent the skin pigmentation, while a* and E represent erythema of skin. We compared the correlation of the two kinds of instrument in skin color measurement of unexposed and exposed sites. And also evaluate their correlation after UV irradiation. Four different UV irradiations were measured, that is, MED, IPD, MPPD and repeated UV irradiation as follows：Day1=1.0 MED, Day2=0.5 MED, Day3=0.5 MED. ResultsWhen measuring the normal skin color, two kinds of instrument showed good correlation. While measuring the skin color after UV irradiation, the L* was more easily affected by erythema than M value. When measuring pigmentation of IPD, MPPD and the pigmentation change course, their correlation are good. a* appeared to be equally effective in measuring the skin erythema response of MED as E. However, when the eryt