活体五谷虫对压疮创面生物清创技术探究.docVIP

活体五谷虫对压疮创面生物清创技术探究(1.大连医科大学附属第一医院,辽宁 大连 116011;2.辽宁中医药大学药学院,辽宁 大连 116001; 3.大连医科大学药学院,辽宁 大连 116044) 摘 要:目的:研究应用活体五谷虫治疗压疮创面的生物清创技术。方法: 11例脊髓损伤后截瘫患者的压疮创面,应用实验室培养的无菌活体五谷虫进行生物清创治疗,取创面分泌物作细菌培养,记录培养结果,观察创面愈合情况。结果:创面分泌物细菌培养逐渐由阳性转为阴性,平均时间11.2天;感染创面脓性分泌物及坏死组织逐渐减少,新鲜肉芽组织形成,平均时间2.6天;创面逐渐缩小,获得良好愈合,平均时间25.6天。结论:活体五谷虫生物清创技术是治疗压疮创面的安全有效的方法。 关键词:五谷虫;生物清创;压疮创面? 中图分类号:R285.5 文献标识码:A 文章编号:1673-7717(2010)04-0741-03 Study of Living Maggot Bio?debridement Technique for Pressure Ulcers WANG Shou?yu1, ZHANG Zhen1, DIAO Yun?peng2-3, Kang Ting?guo2, LU De?cheng1 (1.Department of Orthopedics, 1st Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning,China; 2.College of pharmacy,Liaoning University of Traditional Chinese Medicine, Dalian 116001, Liaoning,China; 3.College of pharmacy, Dalian Medical University, Dalian 116044, Liaoning,China) Abstract:?Objective:?To investigate the application of living maggot bio-debridement technique for treating pressure ulcers. ?Methods:?Eleven cases suffered from pressure ulcers after spinal cord injury were treated with living maggot bio-debridement technique by using aseptic maggots. The changes of ulcers were observed and bacterial culture was tested.?Results:?Negative results were found in the bacterial culture(on average 11.2days), the suppurative and necrotic tissue in the ulcer was declined, fresh granulation tissue was regenerated(on average 2.6 days), and finally all ulcers healed(on average 25.6days). ?Conclusion:? Living maggot bio-debridement technique is a safe and effective method for treating pressure ulcers.? Key words:maggot; bio?debridement; pressure ulcers [FQ(10*2。25,X-W] 收稿日期:2009-11-03 基金项目:国家自然科学基金资助项目30901950) 作者简介:王寿宇(1976-),男,辽宁阜新人,讲师、主治医师,博士,研究方向:中西医结合治疗创面愈合的临床和基础研究。 通讯作者:康廷国(1955-),男,山东寿光人,教授、博士研究生导师,博士,研究方向:创面愈合的中药筛选。 吕德成(1955-),男,辽宁大石桥人,教授、主任医师,博士研究生导师,博士,研究方向:中西医结合治疗创面愈合的临床和基础工作。 压疮创面是临床上常见的疾病,治疗困难。中医学认为:该疾病的基本病因病机是气阴两虚,燥热内结、络脉瘀阻、热毒内蕴,热毒、湿热、瘀血相