LASIK术中负压吸引时间对猪角膜瓣厚度和直径的影响.docVIP

　　LASIK术中负压吸引时间对猪角膜瓣厚度和直径的影响 ：马小力,徐建刚，刘汉强 【摘要】 　　目的：探讨准分子激光原位角膜磨镶术（LASIK）术中负压吸引时间对角膜瓣厚度和直径的影响。方法：根据负压吸引时间的不同将60只猪眼随机分为3组：组1（10s）、组2（20s）和组3（30s），使用法国产Moria M2型角膜板层刀分别吸引角膜10s，20s和30s后切削角膜瓣，利用角膜超声测厚仪测量角膜瓣厚度，应用镀铬游标卡尺测量角膜瓣直径。结果：组1、 2和3角膜瓣厚度分别为146.05±13.46，157.35±18.95和169.25±21.02μm，各组间比较有显著性差异(P＝0.001)。各组的平均角膜瓣直径分别为8.63±0.19mm（组1，10s），8.89±0.24mm（组2，20s）和9.06±0.18mm（组3，30s）。各组间比较有显著性差异(Plt;0.01)。结论：LASIK术中随着负压吸引时间的延长，角膜瓣厚度和直径均增加。 【关键词】 负压吸引；角膜瓣厚度；LASIK 　　Abstract　AIM: To determine the effect of suction duration on thickness and diameter of corneal flap created by microkeratome in porcine eyes in laser in situ keratomileusis (LASIK).METHODS: Sixty porcine eyes ly assigned to three groups according to different suction durations: group 1 (10 seconds), group 2 (20 seconds), and group 3 (30 seconds). A Moria M2 microkeratome (Moria, France) head easured by automated ultrasonic pachymetry, and the flap diameter easured by a vernier caliper.RESULTS: The flap thickness of group 1, group 2 and group 3 , 157.35±18.95μm and 169.25±21.02μm, respectively. There ong three groups (P=0.001). The mean flap diameter in groups 1, 2 and 3 m, 8.89±0.24mm and 9.06±0.18mm, respectively. A statistically significant difference ong groups (Plt;0.01).CONCLUSION: In LASIK in porcine eyes, an increase in suction duration resulted in a thicker and greater flap.  　　KEYATERIALS AND METHODS 　　Materials Porcine eyes a local abattoir. The eyes oist chambers and used for experiments in each eye easurements. Porcine eyes ly assigned to three groups, inations The intraocular pressure(IOP) of porcine eyes al saline through the optic nerve and maintained mHg to 25mmHg. IOP easured eter (TOPCON, Japan). The IOP of each porcine eye easured three times and then averaged. 　　Measurements of central corneal thickness (CCT) and keratometry ed using Micropach 200 automated ultrasonic pachymeter (Sonomed, Japan) and RK3 automatic keratometer (Canon, Japan). The CCT and keratometry of each porci