人乳腺MCF10A细胞系K~+通道的表达和特性及其与增殖的关系.PDF

See discussions, stats, and author profiles for this publication at: /publication [Expression and properties of potassium channels in human mammary epithelial cell line MCF10A and its possible role in... Article in Sheng li xue bao: Acta physiologica Sinica] · June 2010 Source: PubMed CITATIONS READS 6 80 8 authors, including: Shuang Feng Wei Cheng Columbia University Dalian Medical University 7 PUBLICATIONS 59 CITATIONS 26 PUBLICATIONS 81 CITATIONS SEE PROFILE SEE PROFILE Shi-Qiang Wang Peking University 59 PUBLICATIONS 2,27 CITATIONS SEE PROFILE Some of the authors of this publication are also working on these related projects: TRP channels and cancer View project All content following this page was uploaded by Wei Cheng on 21 August 2017. The user has requested enhancement of the downloaded file. 生理学报 Acta Physiologica Sinica, June 25, 2010, 62 (3): 203-209 203 研究论文 人乳腺 MCF10A 细胞系 K+ 通道的表达和特性及其与增殖的 关系 1 1 1 1 1 3 4 1, 2,* 刘佳 ，封爽 ，张磊 ，吴争 ，陈茜 ，程为 ，王世强 ，邹伟 1 2 3 辽宁师范大学生命科学学院，大连 116029 ； 辽宁省生物技术与分子药物研发重点实验室，大连 116029 ； 大连理工大 4 学物理与光电工程学院，大连 116026 ； 北京大学生命科学学院，北京100871 摘 要：近年来发现，K+ 通道与乳腺癌细胞的增殖和转化密切相关，但机制尚不清楚。本研究室前期报道了K+ 通道阻断 剂4- 氨基吡啶(4-aminopyridine, 4-AP)能够抑制人乳腺上皮细胞的增殖，本文则进一步检测几种电压门控K+ 通道(voltage-g