determination of flow conditions in coronary bifurcation lesions in the context of the medina classification流条件下测定冠状动脉分叉病变麦地那的上下文分类.pdfVIP

Hindawi Publishing Corporation Modelling and Simulation in Engineering Volume 2012, Article ID 419087, 10 pages doi:10.1155/2012/419087 Research Article Determination of Flow Conditions in Coronary Bifurcation Lesions in the Context of the Medina Classification Marjan Molavi Zarandi,1 Rosaire Mongrain,1, 2 and Olivier F. Bertrand3, 4 1 Department of Mechanical Engineering, McGill University, Montreal, QC, Canada H3A 0C3 2 Department of Cardiovascular Surgery, Montreal Heart Institute, Montreal, QC, Canada H1T 1C8 3 Quebec Heart-Lung Institute, Laval Hospital, Quebec City, QC, Canada G1V 4G5 4 Faculty of Medicine, Laval University, Quebec City, QC, Canada G1V 0A6 Correspondence should be addressed to Rosaire Mongrain, rosaire.mongrain@mcgill.ca Received 10 January 2012; Accepted 3 March 2012 Academic Editor: Guan Heng Yeoh Copyright © 2012 Marjan Molavi Zarandi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Coronary artery bifurcation lesions are complex and several classifications are presented to describe them. Recently, the Medina classification has been proposed. This classification uses binary values for characterization of stenosis. Flow conditions according to Medina classification have not been described. In this paper, bifurcation lesions corresponding to anatomical Medina lesion classification are compared on the basis of flow and Wall Shear Stress (WSS). Computational models of healthy and stenosed coronary artery bifurcations ((1, 1, 1), (0, 1, 1) and (1, 0, 1)) with moderate and severe stenoses of 50% and 75% diameter were analyzed. The results showed that, flow conditions vary in bi