assessment of fetal autonomic nervous system activity by fetal magnetocardiography comparison of normal pregnancy and intrauterine growth restriction评估胎儿胎儿magnetocardiography自主神经系统活动的比较正常的怀孕和宫内生长受限.pdfVIP

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assessment of fetal autonomic nervous system activity by fetal magnetocardiography comparison of normal pregnancy and intrauterine growth restriction评估胎儿胎儿magnetocardiography自主神经系统活动的比较正常的怀孕和宫内生长受限.pdf

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assessment of fetal autonomic nervous system activity by fetal magnetocardiography comparison of normal pregnancy and intrauterine growth restriction评估胎儿胎儿magnetocardiography自主神经系统活动的比较正常的怀孕和宫内生长受限

Hindawi Publishing Corporation Journal of Pregnancy Volume 2011, Article ID 218162, 6 pages doi:10.1155/2011/218162 Research Article Assessment of Fetal Autonomic Nervous System Activity by Fetal Magnetocardiography: Comparison of Normal Pregnancy and Intrauterine Growth Restriction Akimune Fukushima,1 Kenji Nakai,2 Tomonobu Kanasugi,1 Miyuki Terata,1 and Toru Sugiyama1 1 Department of Obstetrics and Gynecology, School of Medicine, Iwate Medical University, Morioka 020-8505, Japan 2 Department of Dentistry and Internal Medicine, Iwate Medical University, Morioka 020-8505, Japan Correspondence should be addressed to Akimune Fukushima, akimunef@iwate-med.ac.jp Received 14 October 2010; Accepted 8 February 2011 Academic Editor: Marlene Sinclair Copyright © 2011 Akimune Fukushima et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To clarify the developmental activity of the autonomic nervous system (ANS) of the normal fetus and intrauterine growth restriction (IUGR) cases using fetal magnetocardiography (FMCG). Subjects and Methods. Normal pregnancy (n = 35) and IUGR (n = 12) cases at 28–39 and 32–37 weeks of gestation, respectively, were included in this study. The R-R interval variability was used to calculate the coeﬃcient of variance (CVRR ) and low frequency/high frequency (LF/HF) ratio. Results. The value of CVRR in the normal pregnancy group displayed a slight increasing trend with gestational age. However, no such trend was observed in the IUGR group. In contrast, the LF/HF ratio in both the normal pregnancy group and the IUGR group clearly increased over the gestat