assessment of toxicity of some penta- and hexacoordinated organotin(iv) and tetracoordinated tin(ii) complexes of heterocyclic -diketones一些表示u201c五u201d和毒性评估hexacoordinated有机锡(iv)和杂环-diketones tetracoordinated锡(ii)配合物.pdfVIP

Hindawi Publishing Corporation Bioinorganic Chemistry and Applications Volume 2006, Article ID 60140, Pages 1–4 DOI 10.1155/BCA/2006/60140 Assessment of Toxicity of Some Penta- and Hexacoordinated Organotin(IV) and Tetracoordinated Tin(II) Complexes of Heterocyclic β-Diketones Asha Jain,1 Sanjiv Saxena,1 Audhesh K. Rai,1 and Prabhu N. Saxena2 1 Department of Chemistry, University of Rajasthan, Jaipur 302004, India 2 Department of Zoology, Toxicology Laboratory, School of Life Sciences, Dr. B.R. Ambedkar University, Agra 282004, India Received 4 May 2004; Accepted 9 September 2004 A number of penta- and hexacoordinated organotin(IV) complexes and tetracoordinated tin(II) complexes of compositions Me SnCl[RCOC:CON(C H )N:CCH ] (where R = −CH , −p−ClC H , and −C H ), Me Sn[RCOC : CON(C H )N : CCH ] 2 6 5 3 3 6 4 6 5 2 6 5 3 2 (where R = −CH , and −C H ), and Sn(II) [RCOC : CON(C H )N : CCH ] (where R = −p−ClC H and −C H ) were 3 6 5 6 5 3 2 6 4 6 5 screened for their toxicity against Musca domestica (house fly). In general, organotin(IV) complexes contribute more to the activity than tin(II) complexes. Copyright © 2006 Asha Jain et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. INTRODUCTION EXPERIMENTS There has been considerable interest in the chemistry of The organ