automatic determination of ms lesion subtypes based on fractal analysis in brain mr images自动确定病变亚型女士先生基于分形分析的大脑图像.pdfVIP

J. Biomedical Science and Engineering, 2012, 5, 162-169 JBiSE / 10.4236/jbise.2012.54021 Published Online April 2012 (http://www.SciRP.org/journal/jbise/) Automatic determination of MS lesion subtypes based on fractal analysis in brain MR images Mahdi Mohamadkhanloo, Farzad Mehrabi, Abdolhamid Sohrabi Department of Medical Science, Aja University, Tehran, Iran Email: mahdi.khanlo@, df_mehrabi2002@, sohrabind@ Received 29 November 2011; revised 25 December 2011; accepted 29 January 2012 ABSTRACT of MS is MRI. Recently, the study of MRI in MS has been flourishing in the field of research due to its ability In this paper a novel approach based on fractal in generating multiple images of the same tissue with analysis has been proposed to determine MS lesions different contrast mechanisms using different image ac- into two subtypes (i.e., Enhancing lesions (Acute), T1 quisition protocols and parameters. In its application to “black holes” (chronic) lesions) in Fluid Attenuated MS, macroscopic areas of damage or loss of myelin with Inversion Recovery (FLAIR) MR images, automati- hyper or hypo intensities relative to the surrounding tis- cally. In the proposed method, firstly, MS lesion vox- sues are shown by MRI. Differe