changing trends in colorectal cancer possible cause and clinical implications变化趋势在结直肠癌的可能原因及临床意义.pdfVIP

Vol.2, No.8, 842-849 (2010) HEALTH doi:10.4236/health.2010.28127 Changing trends in colorectal cancer: possible cause and clinical implications 1 2 1 3 Mikhail Fisher , Leon Fisher , Bruce Waxman , Alexander A. Fisher * 1Academic Surgical Unit, Monash University, Dandenong Hospital, Southern Health, Melbourne, Australia 2Department of Gastroenterology, Peninsula Health, Frankston, Australia 3Division of Medicine, The Canberra Hospital and Australian National University Medical School, Canberra, Australia; *Corresponding Author: alex.fisher@.au Received 18 April 2010; revised 4 May 2010; accepted 6 May 2010. ABSTRACT screening and preventive strategies and on demand for radiotherapy services. OBJECTIVES: The aims of this study were to determine whether pattern of patients present- Keywords: Colorectal Cancer; Age; Gender; ing with colorectal cancer (CRC) in the last few Hormone Replacement Therapy; Trends years differs significantly from that previously reported in Australia, and to relate the trends, if present, to use of hormone replacement therapy 1. INTRODUCTION (HRT). METHODS: We examined demographic and pathological characteristics of 145 con- Colorectal cancer (CRC) is the most prevalent non-skin secutive CRC patients (65 females) treated in malignancy and second highest cause of cancer-related our institution in calendar years 2006-2007. death in Australia [1] as in other industrialized countries. Comparisons were mad