clinicopathological analysis of patients with nonmuscle-invasive bladder cancer who underwent radical cystectomy临床病理的分析例行根治性膀胱切除术nonmuscle-invasive膀胱癌患者.pdfVIP
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clinicopathological analysis of patients with nonmuscle-invasive bladder cancer who underwent radical cystectomy临床病理的分析例行根治性膀胱切除术nonmuscle-invasive膀胱癌患者
Surgical Science, 2012, 3, 347-352
/10.4236/ss.2012.37068 Published Online July 2012 (http://www.SciRP.org/journal/ss)
Clinicopathological Analysis of Patients with
Nonmuscle-Invasive Bladder Cancer Who Underwent
Radical Cystectomy
1,2* 2 1 1 3
Naotaka Nishiyama , Hiroshi Kitamura , Masatoshi Mutoh , Masahiro Yanase , Hiroyuki Iwaki ,
Tadashi Hasegawa4, Taiji Tsukamoto2
1Divisions of Urology, Sunagawa City Medical Center, Sunagawa, Japan
2Departments of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan
3Divisions of Pathology, Sunagawa City Medical Center, Sunagawa, Japan
4Departments of Surgical Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan
Email: nishiyan@sapmed.ac.jp
Received May 26, 2012; revised June 16, 2012; accepted June 26, 2012
ABSTRACT
Objectives: Surgical specimens obtained at the time of the last transurethral resection of bladder tumor (TURBT) for
patients with nonmuscle-invasive bladder cancer (NMIBC) who underwent radical cystectomy were retrospectively
evaluated in order to investigate the relationship between pathological variation and upstaging of NMIBC. Methods
and Materials: Twenty patients (19 men, 1 woman; aged 69.4 ± 12.1 (mean ± SD) years) diagnosed with NMIBC un-
derwent radical cystectomy during follow-up. Results: Five of the 20 patients (25%) had pathological upstaging in the
radical cystectomy specimens. There was a statistical association between pathological upstaging and cancer death (p =
0.002). Ther
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