clinicopathological analysis of patients with nonmuscle-invasive bladder cancer who underwent radical cystectomy临床病理的分析例行根治性膀胱切除术nonmuscle-invasive膀胱癌患者.pdfVIP

clinicopathological analysis of patients with nonmuscle-invasive bladder cancer who underwent radical cystectomy临床病理的分析例行根治性膀胱切除术nonmuscle-invasive膀胱癌患者.pdf

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clinicopathological analysis of patients with nonmuscle-invasive bladder cancer who underwent radical cystectomy临床病理的分析例行根治性膀胱切除术nonmuscle-invasive膀胱癌患者

Surgical Science, 2012, 3, 347-352 /10.4236/ss.2012.37068 Published Online July 2012 (http://www.SciRP.org/journal/ss) Clinicopathological Analysis of Patients with Nonmuscle-Invasive Bladder Cancer Who Underwent Radical Cystectomy 1,2* 2 1 1 3 Naotaka Nishiyama , Hiroshi Kitamura , Masatoshi Mutoh , Masahiro Yanase , Hiroyuki Iwaki , Tadashi Hasegawa4, Taiji Tsukamoto2 1Divisions of Urology, Sunagawa City Medical Center, Sunagawa, Japan 2Departments of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan 3Divisions of Pathology, Sunagawa City Medical Center, Sunagawa, Japan 4Departments of Surgical Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan Email: nishiyan@sapmed.ac.jp Received May 26, 2012; revised June 16, 2012; accepted June 26, 2012 ABSTRACT Objectives: Surgical specimens obtained at the time of the last transurethral resection of bladder tumor (TURBT) for patients with nonmuscle-invasive bladder cancer (NMIBC) who underwent radical cystectomy were retrospectively evaluated in order to investigate the relationship between pathological variation and upstaging of NMIBC. Methods and Materials: Twenty patients (19 men, 1 woman; aged 69.4 ± 12.1 (mean ± SD) years) diagnosed with NMIBC un- derwent radical cystectomy during follow-up. Results: Five of the 20 patients (25%) had pathological upstaging in the radical cystectomy specimens. There was a statistical association between pathological upstaging and cancer death (p = 0.002). Ther

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