cognitive and psychological outcomes in younger vs. older children with subtentorialsupratentorial ependymoma after radiation therapy在年轻和年长的孩子认知和心理结果subtentorialsupratentorial放疗后室管膜瘤.pdfVIP

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cognitive and psychological outcomes in younger vs. older children with subtentorialsupratentorial ependymoma after radiation therapy在年轻和年长的孩子认知和心理结果subtentorialsupratentorial放疗后室管膜瘤.pdf

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cognitive and psychological outcomes in younger vs. older children with subtentorialsupratentorial ependymoma after radiation therapy在年轻和年长的孩子认知和心理结果subtentorialsupratentorial放疗后室管膜瘤

Journal of Behavioral and Brain Science, 2011, 1, 87-93 doi:10.4236/jbbs.2011.13012 Published Online August 2011 (http://www.SciRP.org/journal/jbbs) Cognitive and Psychological Outcomes in Younger vs. Older Children with Subtentorial/Supratentorial Ependymoma after Radiation Therapy 1 1 2 1 Geraldina Poggi , Annarita Adduci , Lorenza Gandola , Susanna Galbiati , Alessandro Degrate1 1 1 2 , Elena Sironi , Sandra Strazzer , Maura Massimino 1Scientific Institute E. Medea, Bosisio Parini, Italy 2National Tumor Institute, Milan, Italy E-mail : geraldina.poggi@bp.lnf.it Received March 28, 2011; revised April 20, 2011; accepted May 12, 2011 Abstract Purpose: to investigate cognitive and psychological problems in children treated for intracranial ependy- moma, the evolution of these disorders over time and the role of age at radiotherapy and tumor site, in their onset and persistence. Methods and Materials: 23 patients received a complete evaluation; some of them underwent follow-ups. The clinical data collected included sex, age (at diagnosis, assessment and tumor treatment, thus dividing patients into two cohorts: younger or older than 5 years), site (supratentorial vs. sub- tentorial), the presence of hydrocephalus, neurological examination, tumor treatment. All the patients re- ceived an age-appropriate cognitive and psychological evaluation. Results: The mean cognitive level was within the norm, with lower scores on the