原创力文档comparative evaluation of the efficacy of the bimatoprost 0.03%, brimonidine 0.2%, brinzolamide 1%, dorzolamide 2%, and travoprost 0.004%timolol 0.5%-fixed combinations in patients affected by open-angle glaucoma英文论文.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
comparative evaluation of the efficacy of the bimatoprost 0.03%, brimonidine 0.2%, brinzolamide 1%, dorzolamide 2%, and travoprost 0.004%timolol 0.5%-fixed combinations in patients affected by open-angle glaucoma英文论文
Open Journal of Ophthalmology, 2012, 2, 122-126
/10.4236/ojoph.2012.24027 Published Online November 2012 (http://www.SciRP.org/journal/ojoph)
Comparative Evaluation of the Efficacy of the Bimatoprost
0.03%, Brimonidine 0.2%, Brinzolamide 1%, Dorzolamide
2%, and Travoprost 0.004%/Timolol 0.5%-Fixed
Combinations in Patients Affected by Open-Angle
*
Glaucoma
Italo Giuffre
Department of Ophthalmology, Medical School, Catholic University of Rome, Rome, Italy.
Email: italogiuffre@libero.it
Received July 20th, 2012; revised September 22nd, 2012; accepted October 30th, 2012
ABSTRACT
Purpose: This is a retrospective, comparative, head-to-head, not commissioned study about the efficacy of bimatoprost
0.03%, brimonidine 0.2%, brinzolamide 1%, dorzolamide 2%, and travoprost 0.004%/timolol 0.5%-fixed combinations
in patients affected by naΐve open-angle glaucoma and IOP 25 mmHg. Patients and Methods: Files from 70 patients
(35 M, 35 F, mean age 69.52 y, S.D. 11.56, range: 37 - 87 y) in our Glaucoma Service were retrospectively analyzed as
long as 12 months. Every subgroup, including 14 age- and sex-matched patients, was allocated to 1 of the 5 groups of
the fixed combinations monotherapy. Data recorded after 3 months follow-up were statistically analyzed by descriptive
and ANOVA statistics as percentage of IOP reduction from baseline. Results: All the fixed combinations were effective
in lowering IOP. The mean percentage reduction was: brimonidine/timolol 43.57%, dorzolamide/timolol 37.67%, bi-
matoprost/timolol 35.60%, travoprost/timolol 33.25% and brinzolamide/timolol 23.0%. The brimonidine/timolol fixed
combination showed to be statistically significant more effective only than brinzolamide/timolol fixed combination (p =
0.001). Setting the α error to 5%, the power of the study is 26%, phi: 0.842. Discussion: In all this cohort of patients the
target IOP was successfully achieved. All the fixed combinations used in this study h
您可能关注的文档
- clinical efficacy of anti-mullerian hormone inspection in supporting diagnosis for climacteric disorders临床疗效在支持她们血液中的抗苗勒氏管激素检查诊断为更年期障碍.pdf
- clinical evaluation of efficacy and safety of a herbal formulation in benign prostatic hyperplasia a single blind, randomized, placebo-controlled study临床评估的有效性和安全性的草药配方良性前列腺增生单一盲,随机,安慰剂对照研究.pdf
- clinical implications and management of sub clinical hyperthyroidism a review亚临床甲亢的临床意义和管理评审.pdf
- clinical management of gastrointestinal amyloidosis胃肠道淀粉样变的临床管理.pdf
- clinical interaction between brain and kidney in small vessel disease临床脑小血管疾病和肾脏之间的相互作用.pdf
- chordomas and their consideration in the radiographic differential of extra-axial lesions of the central nervous摘要脊索瘤和他们考虑的射线微分extra-axial中枢神经的病变.pdf
- classification theorem on irreducible representations of the -deformed algebra在变形的不可约表示代数分类定理.pdf
- clinical predictors of prolonged hospital stay after acute stroke relevance of medical complications临床预测长期住院急性中风后并发症的相关性.pdf
- clinical presentation and outcome in patients of over 75 years old with malignant lymphoma—clinical presentation and outcome in elderly lymphoma patients临床表现和结果在超过75岁的患者恶性lymphoma-clinical老年淋巴瘤患者的表现和结果.pdf
- clinical psychophysical assessment of the on- and off-systems of the magnocellular and parvocellular visual pathways临床心理物理的评估,off-systems magnocellular和parvocellular视觉通路.pdf
- comparative evaluation of permissiveness to dengue virus serotype 2 infection in primary rodent macrophages比较评估的放纵登革2型病毒感染主要啮齿动物巨噬细胞.pdf
- comparative gene expression analysis in stems of dolichos purpureus and arabidopsis thaliana比较基因表达分析白紫色的茎和拟南芥.pdf
- comparative evaluation of the safety and efficacy of long-term use of imidafenacin and solifenacin in patients with overactive bladder a prospective, open, randomized, parallel-group trial (the list study)英文论文.pdf
- comparative analysis of power-law fin-type problems using variational iteration method and finite element method比较分析幂律的鳍状飞问题使用变分迭代法和有限元法.pdf
- comparative evaluation of whole body and hepatic insulin resistance using indices from oral glucose tolerance test in morbidly obese subjects with nonalcoholic fatty liver disease比较评估的整个身体和肝胰岛素抵抗指数在病态肥胖受试者口服葡萄糖耐量试验与非酒精性脂肪肝病.pdf
- comparative evaluation of semi fragile watermarking algorithms for image authentication比较评价图像半脆弱水印算法的验证.pdf
- comparative genomics uncovers large tandem chromosomal duplications in mycobacterium bovis bcg pasteur比较基因组学揭示大串联染色体复制牛结核分枝杆菌卡介苗巴斯德.pdf
- comparative analysis of structure and sequences of oryza sativa superoxide dismutase的结构和序列比较分析栽培稻超氧化物歧化酶.pdf
- comparative in vitro osteoinductivity study of cap ceramics (ha, α-tcp, β-tcp) using 10t12 cells with different controls and possible correlations with other systems比较体外osteoinductivity帽的研究陶瓷(哈,α-tcp,β-tcp)使用10病人细胞具有不同的控制和与其他系统可能的相关性.pdf
- comparative kinetics of immune responses and changes in cellular sub-sets detected in colorectal cancer patients vaccinated with mva-5t4 (trovax) administered alongside two different chemotherapy regimens英文论文.pdf
文档评论（0）