comparison of the proteomes of three yeast wild type strains cen.pk2, fy1679 and w303蛋白质组的比较三种酵母野生型菌株岑。.pdfVIP

Comparative and Functional Genomics Comp Funct Genom 2001; 2: 207–225. DOI: 10.1002 / cfg.94 Research Article Comparison of the proteomes of three yeast wild type strains: CEN.PK2, FY1679 and W303 1 1 2 3 Adelina Rogowska-Wrzesinska *, Peter Mose Larsen , Anders Blomberg , Angelika Go¨rg , Peter Roepstorff4, Joakim Norbeck5 and Stephen John Fey 1 1Centre for Proteome Analysis in Life Sciences, University of Southern Denmark, International Science Park Odense, Forskerparken 10B, 523 Odense M, Denmark 2 Deptartment of Cell and Molecular Biology – Microbiology Lundbergs Laboratory, Go¨teborg University, Medicinaregatan 9C 405 3 0Go¨teborg, Sweden 3 Technical University of Munich, Institute of Food Technology and Analytical Chemistry, Proteomics Group, D-8535 0Freising-Weihenstephan, Germany 4 Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense University, Campusvej 55, 523 0Odense M, Denmark 5 Institut fuer Biochemie und Molekulare Zellbiologie, Universita¨t Wien, Dr-Bohrgasse 9 A-103 0Vienna, Austria *Correspondence to: Abstract A. Rogowska-Wrzesinska, Centre for Proteome Analysis in Life Yeast deletion strains created during gene function analysis projects very often show Sciences, University of Southern drastic phenotypic differences depending on the genetic background used. These results Denmark, International Science indicate the existence of important molecular differences between the CEN.PK2, FY1679 Park Odense, Forskerparken 10B, and W303 wild type strains. To characterise these differences we have compared the 523 0Odense M, Denmark. protein expression levels between CEN.PK2, FY1679 and W303 strain