原创力文档estimated additional lifetime risk of cancer attributable to diagnostic ct in a pediatric bone marrow transplant cohort experience at a single academic institution估计额外一生患癌症的风险由于ct在诊断小儿骨髓移植组在一个学术机构的经历.pdfVIP
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estimated additional lifetime risk of cancer attributable to diagnostic ct in a pediatric bone marrow transplant cohort experience at a single academic institution估计额外一生患癌症的风险由于ct在诊断小儿骨髓移植组在一个学术机构的经历
Open Journal of Clinical Diagnostics, 2012, 2, 4-9 OJCD
/ 10.4236/ojcd.2012.21002 Published Online March 2012 (http://www.SciRP.org/journal/ojcd/)
Estimated additional lifetime risk of cancer attributable to
diagnostic CT in a pediatric bone marrow transplant
cohort: Experience at a single academic institution
1* 2 1
Jonathan O. Swanson , Adam Alessio , Teresa Chapman
1Department of Radiology, Seattle Children’s Hospital/University of Washington, Seattle, USA
2Department of Radiology, University of Washington, Seattle, USA
*
Email: jonathan.swanson@
Received 5 December 2011; revised 21 December 2011; accepted 2 February 2012
ABSTRACT Keywords: Ionizing Radiation; Effective Dose; CT;
Lifetime Additional Risk
Purpose: To determine the frequency of CT proce-
dures in a cohort of bone marrow transplant patients
and estimate the effective dose from each CT proce- 1. INTRODUCTION
dure as well as rough estimates of lifetime attribut-
The evolution of computed tomography technology in
able risk (LAR) of cancer (both incidence and mor-
the last 20 years has markedly improved our ability to
tality). Background: Pediatric patients who undergo
image children. CT innovations have decreased scanning
bone marrow transplant benefit greatly from the di-
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