青少年腰高比及代谢综合征相关性探究.docVIP

青少年腰高比及代谢综合征相关性探究【摘要】 目的 探讨腰高比与青少年代谢综合征的相关性，为代谢综合征的预防提供理论依据。方法 以全国9个城市城乡中学初一、初二、高一、高二学生和省属大学大一、大二学生作为目标人群，对其进行体格检查，并按照知情同意的原则，检测部分目标人群的空腹血糖和血脂。共获得有效人体测量和血压样本12 106份，获得有效空腹血样7 738份。以腰高比≥0.05作为高腰高比的划界标准，按照国际糖尿病联盟提出的儿童青少年代谢综合征诊断标准筛选代谢综合征；运用χ2检验和单因素Logistic回归分析方法分析腰高比与代谢综合征的相关性。结果 青少年代谢综合征检出率为2.0%，高腰高比检出率为7.4%，性别差异均无统计学意义。高腰高比组代谢综合征检出率（14.7%）显著高于对照组（0.8%）（χ2=592.63，P＜0.01），对照组和高腰高比组具有1个代谢综合征症状的比例分别为31.8%和43.8%，有2个代谢综合征症状的比例分别为7.4%和39.9%。高腰高比与代谢综合征之间关联的OR值为6.84（95%CI=4.366～11.889），与中心性肥胖、血压偏高、高三酰甘油和低高密度脂蛋白检出率的正相关均有统计学意义（P＜0.05）。结论 高腰高比与代谢综合征及其症状均有较好的相关性，并且能较好的反映体脂的中心性分布情况。 【关键词】 生长和发育；代谢综合征X；血压；血糖；青少年 【中图分类号】 R 179 R 589.2 【文献标识码】 A 【文章编号】 1000-9817(2009)04-0298-04 Relationship of Waist to Height Ratio and Metabolic Syndrome in Adolescents/QI Xiu-yu, TAO Fang-biao, WAN Yu-hui, et al. Department of Maternal and Child Health of Anhui Medical University, Hefei (230032), China. 【Abstract】 ObjectiveTo study the relationship of waist-to-height ratio and metabolic syndrome(MS) in adolescents, and to provide evidence for MS prevention. MethodsThe study population was a nationwide respective sample of 12 106 adolescents from 9 cities in different provinces. Anthropometric measure and blood pressure were measured and 7 738 fasting serum were collected in accordance with the principle of informed consent. Waist-to-height ratio was calculated by waist circumference and height. Fasting plasma glucose (FPG), triglycerides (TG) and high-density lipoprotein cholesterol (HDL) were measured with auto-analyzer. Waist-to-height ratio that exceeded 0.5 was defined as high waist-to-height ratio. The metabolic syndrome was determined using the diagnostic criteria for children and adolescents which developed by international diabetes federation (IDF). Chi-square test and ANOVA was used to analyze the relationship of waist-to-height ration and metabolic syndrome. ResultsThe overall prevalence of metabolic syndrome in Chinese adolescents was 2.0%, and the overall prevalence of high wa