致病性黏附.pptVIP

一端有2-6根鞭毛，运动活泼的革兰氏阴性螺杆菌 主要生化鉴定依据：脲素酶、过氧化氢酶、氧化酶均为阳性 * * * * * * 尿毒症 uremic 肠道杆菌 Enterobacteriaceae (肠杆菌科) 肠杆菌科目前有44个菌属、170多个种。 多为肠道正常菌群，但可成为条件致病菌；少数为致病菌。 All bacilli belonging to Enterobacteriaceae are short gram-negative rods, either mobile or non-mobile. All bacilli belonging to Enterobacteriaceae are facultative anaerobes. They grow in common media. Most of the enteric bacilli form round, convex, smooth colonies with distinct edges. Lactose（乳糖） fermentation Mechanism: Non-pathogenic enteric bacilli can ferment lactose while pathogenic enteric bacilli such as Shigella and Salmonella can not. Media: SS-plate or EMB plate , TSI agar slants Basic components: lactose and a pH indicator The identification of Enterobacteriaceae is largely depend on biochemical reactions Results SS plate red colonies non-pathogenic/非致病菌 white colonies pathogenic/致病菌 Enterobacteriaceae have complex antigenic structures. H Ag (flagella) somatic O Ag (lipopolysaccharide) K/Vi Ag (capsule) Common pathogenic materials for Enterobacteriaceae include: bacterial structures (pili, capsule) toxins (enterotoxin, endotoxin) Infections outside the intestines caused by bacterial translocation Opportunistic infection including septicemia, pneumonia, meningitis and urinary tract infections Community-acquired infection urinary tract infections E. coli associated urinary tract infection E. coli causes urinary tract infections such as acute cystitis（急性膀胱炎） and pyelonephritis（肾盂肾炎）. Infections inside the intestines caused by pathogenic E. coliCommon symptoms include Gastroenteritis（肠胃炎）, diarrhea（腹泻） and dysentery（痢疾）. Disease transmission is by fecal-oral route （粪口途径）. Enterotoxigenic E. coli (ETEC/肠产毒性大肠杆菌) Enteropathogenic E. coli (EPEC/肠致病性大肠杆菌) Enteroinvasive E. coli (EIEC/肠侵袭型大肠杆菌) Enterohemorrhagic E. coli (EHEC/肠出血性大肠杆菌) Enteroaggregative E. coli (EAEC/肠集聚性大肠杆菌) Cause traveller’s diarrhea. Two types of plasmid-encoded toxins are produced: Heat labile