action of coriandrum sativum l. essential oil upon oral candida albicans biofilm formationcoriandrum作用一种l .精油在口腔白色念珠菌生物膜的形成.pdfVIP
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action of coriandrum sativum l. essential oil upon oral candida albicans biofilm formationcoriandrum作用一种l .精油在口腔白色念珠菌生物膜的形成
Hindawi Publishing Corporation
Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 985832, 9 pages
doi:10.1155/2011/985832
Research Article
Action of Coriandrum sativum L. Essential Oil upon
Oral Candida albicans Biofilm Formation
V. F. Furletti,1, 2 I. P. Teixeira,1, 2 G. Obando-Pereda,1, 2 R. C. Mardegan,1, 2 A. Sartoratto,2
2 2 2 2 ¨ 1
G. M. Figueira, R. M. T. Duarte, V. L. G. Rehder, M. C. T. Duarte, and J. F. Hofling
1 Department of Microbiology and Immunology, Dental School of Piracicaba, University of Campinas-UNICAMP,
13414-903 Piracicaba, SP, Brazil
2 Research Center for Chemistry, Biology and Agriculture, University of Campinas-UNICAMP, P.O. Box 6171,
13083-970 Campinas, SP, Brazil
Correspondence should be addressed to V. F. Furletti, vivifurletti@.br
Received 10 February 2011; Accepted 17 March 2011
Copyright © 2011 V. F. Furletti et al. This is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The efficacy of extracts and essential oils from Allium tuberosum, Coriandrum sativum, Cymbopogon martini, Cymbopogon
winterianus, and Santolina chamaecyparissus was evaluated against Candida spp. isolates from the oral cavity of patients with
periodontal disease. The most active oil was fractionated and tested against C. albicans biofilm formation. The oils were obtained
by water-distillation and the extracts were prepared with macerated dried plant material. The Minimal Inhibitory Concentration—
MIC was determined by the mi
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