activation of right ventral prefrontal cortex using a predictive cue during visual spatial orienting of attentional processes an fmri study使用预测提示激活右腹侧前额叶皮层在视觉空间注意的过程的功能磁共振成像研究的方向.pdfVIP

Hindawi Publishing Corporation Neurology Research International Volume 2012, Article ID 961342, 7 pages doi:10.1155/2012/961342 Clinical Study Activation of Right Ventral Prefrontal Cortex Using a Predictive Cue during Visual Spatial Orienting of Attentional Processes: An fMRI Study Chunlin Li and Jinglong Wu Biomedical Engineering Laboratory, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan Correspondence should be addressed to Jinglong Wu, wu@mech.okayama-u.ac.jp Received 9 January 2012; Accepted 15 February 2012 Academic Editor: Tetsuo Touge Copyright © 2012 C. Li and J. Wu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Visual spatial orienting of attention can be investigated with location-cueing paradigms in which a cue provides correct information about the location of the upcoming target. Target detection is facilitated when the target appears at the expected cued location. In this study, we examined the brain activation of the spatial orienting response based on attentional “benefits.” During an fMRI experiment, two types of attentional tasks were used. Both predictive and nonpredictive cues were used and followed by an upcoming target. Behavioral data showed a faster reaction time with the predictive cue when compared with that of the nonpredictive cue. The fMRI results of these two tasks were compared, whereby isolated brain areas activated when the targets appeared at the attended position after a specific spatial expectation was induced by the cue were compared with when equivalent targets appeared after no spatial expectation was ind