advances in wound healing a review of current wound healing products伤口愈合伤口愈合进展回顾当前的产品.pdfVIP

Hindawi Publishing Corporation Plastic Surgery International Volume 2012, Article ID 190436, 8 pages doi:10.1155/2012/190436 Review Article Advances in Wound Healing: A Review of Current Wound Healing Products Patrick S. Murphy and Gregory R. D. Evans Aesthetic and Plastic Surgery Institute, University of California Irvine Medical Center, 200 S. Manchester Avenue, Suite 650, Orange, CA 92868, USA Correspondence should be addressed to Patrick S. Murphy, pmurphy02@ Received 9 December 2011; Accepted 16 January 2012 Academic Editor: Bishara S. Atiyeh Copyright © 2012 P. S. Murphy and G. R. D. Evans. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Successful wound care involves optimizing patient local and systemic conditions in conjunction with an ideal wound healing environment. Many different products have been developed to influence this wound environment to provide a pathogen-free, protected, and moist area for healing to occur. Newer products are currently being used to replace or augment various substrates in the wound healing cascade. This review of the current state of the art in wound-healing products looks at the latest applications of silver in microbial prophylaxis and treatment, including issues involving resistance and side effects, the latest uses of negative pressure wound devices, advanced dressings and skin substitutes, biologic wound products including growth factor applications, and hyperbaric oxygen as an adjunct in wound healing. With the abundance of available products, the goal is to find the most appropriate modality or combination of modalities to optimize healing.