b-type natriuretic peptide in the critically ill with acute kidney injuryb型利钠肽在急性肾损伤的危重.pdfVIP

SAGE-Hindawi Access to Research International Journal of Nephrology Volume 2011, Article ID 951629, 6 pages doi:10.4061/2011/951629 Research Article B-Type Natriuretic Peptide in the Critically Ill with Acute Kidney Injury Massimo de Cal,1, 2 Mikko Haapio,1, 3 Dinna N. Cruz,1 Paolo Lentini,1, 2 Andrew A. House,1, 4 1 ` 1 1 1 5 Ilona Bobek, Grazia M. Virzı, Valentina Corradi, Flavio Basso, Pasquale Piccinni, Angela D’Angelo,2 Jamie W. Chang,6 Mitchell H. Rosner,6 and Claudio Ronco1 1 Department of Nephrology, San Bortolo Hospital, 36100 Vicenza, Italy 2 Division of Nephrology, University of Padua, 35122 Padua, Italy 3 Division of Nephrology, Meilahti Hospital, HUCH, 00029 Helsinki, Finland 4 Division of Nephrology, London Health Sciences Center, London ON, Canada N6A 5A5 5 Intensive Care Unit, San Bortolo Hospital, 36100 Vicenza, Italy 6 Division of Nephrology, University of Virginia Health System, Charlottesville, VA 22908, USA Correspondence should be addressed to Dinna N. Cruz, dinnacruzmd@ Received 20 July 2010; Revised 12 January 2011; Accepted 25 April 2011 Academic Editor: Anjay Rastogi Copyright © 2011 Massimo de Cal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Acute kidney injury (AKI) is common in the intensive care unit (ICU) and associated with poor outcome. Plasma B-type natriuretic peptide (BNP) is a biomarker related to myocardial overload, and is elevated in some ICU patients