sleep apnea and cognitive function in heart failure睡眠呼吸暂停和认知功能在心力衰竭.pdf

Hindawi Publishing Corporation Cardiovascular Psychiatry and Neurology Volume 2012, Article ID 402079, 7 pages doi:10.1155/2012/402079 Clinical Study Sleep Apnea and Cognitive Function in Heart Failure Krysten M. Knecht,1 Michael L. Alosco,1 Mary Beth Spitznagel,1, 2 Ronald Cohen,3 Naftali Raz,4 Lawrence Sweet,3 Lisa H. Colbert,5 Richard Josephson,6 Joel Hughes,1, 2 Jim Rosneck,2 and John Gunstad1, 2 1 Department of Psychology, Kent State University, Kent, OH 44242, USA 2 Department of Psychiatry, Summa Health System, Akron, OH 44304, USA 3 Institute for Brain Sciences, Brown University, Providence, RI 02912, USA 4 Institute of Gerontology, Wayne State University, Detroit, MI 48201, USA 5 Institute on Aging, University of Wisconsin—Madison, Madison, WI 53706, USA 6 Harrington Heart Vascular Institute, University Hospitals Case Medical Center and Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA Correspondence should be addressed to John Gunstad, jgunstad@ Received 20 January 2012; Revised 13 April 2012; Accepted 16 April 2012 Academic Editor: Heimo Viinamaki Copyright © 2012 Krysten M. Knecht et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Prior research indicates that heart failure (HF) patients exhibit significant cognitive deficits on neuropsychological testing. Sleep apnea is associated with both HF and reduced cognitive function, but the combined impact of these conditions on cognitive function is unknown. Methods. In the current study, 172 older adults with a dual diagnosis of HF and sleep apne