stability-indicating gradient rp-lc method for the determination of process and degradation impurities in bosentan monohydrate an endothelin receptor antagoniststability-indicating梯度rp-lc过程和降解杂质的测定方法应用波生坦一水内皮素受体拮抗剂.pdfVIP

SAGE-Hindawi Access to Research Chromatography Research International Volume 2011, Article ID 929876, 9 pages doi:10.4061/2011/929876 Research Article Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist Sanjay A. Jadhav,1 Shashikant B. Landge,1 Sonali L. Jadhav,1 Navanath C. Niphade,1 Saroj R. Bembalkar,2 and Vijayavitthal T. Mathad1 1 Research and Development, Megafine Pharma (P) Ltd., Nashik 422 202, India 2 Department of Chemist