ginsenoside rb1 prevents mpp+-induced apoptosis in pc12 cells by stimulating estrogen receptors with consequent activation of erk12, akt and inhibition of sapkjnk, p38 mapk人参皂苷rb1防止mpp +全身的细胞凋亡在pc12细胞通过刺激雌激素受体的激活erk12,akt和抑制sapkjnk p38 mapk.pdfVIP

Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2012, Article ID 693717, 8 pages doi:10.1155/2012/693717 Research Article Ginsenoside Rb1 Prevents MPP+-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, p38 MAPK Ryo Hashimoto,1, 2 Jing Yu,1 Hideki Koizumi,1 Yasuyoshi Ouchi,2 and Tetsuro Okabe1 1 Department of Integrated Traditional Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tok