变异链球菌耐氟菌株探究进展.docVIP

变异链球菌耐氟菌株探究进展[摘要]氟化物作为防龋制剂，其广泛应用可能导致变异链球菌耐氟菌株的产生。为了解变异链球菌耐氟菌株致龋毒力的变化，学者们对其超微结构、黏附力、耐酸性、产酸性及脱矿能力等致龋相关特性进行了研究，并对耐氟菌株的致龋相关基因和其他分子生物学改变予以深入的研究和探讨。本文就此作一综述。 [关键词]变异链球菌；耐氟菌株；致龋性；致龋相关基因 [中图分类号]R 780.2[文献标志码]A[doi]10.3969/j.issn.1673-5749.2012.03.017 Research progress on fluoride-resistant strains of Streptococcus mutansWu Yeke, Hu Tao.（State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China） [Abstract]As a caries-preventive agent, fluoride could probably lead to fluoride-resistant strains of Streptococcus mutans（S.mutans）with its wide application in the daily life