填空与名词解释（Fill in the blanks and explain the noun）.docVIP

填空与名词解释（Fill in the blanks and explain the noun） First, fill in the blanks or explain the nouns: 1 、 the unstable structure of procaine hydrochloride has ester bond and (aryl) amino group, which can react (reaction) and react (reaction) under certain conditions. 2, Aspirin structure contains (ester bond), and thus easy to water (hydrolysis), the product is (salicylic acid and acetic acid). 3, nitro compounds often produce (primary amines) metabolites when they undergo reductive metabolic reactions in vivo. 4, when the heterocyclic drugs were oxidized and metabolized, the changes in their rings showed (Qiang Jihua). 5. Isoniazid, due to the structure of hydrazine (hydrazine), is easily hydrolyzed under acid or alkali to produce (ISO nicotinic acid) and (hydrazine), so it is more toxic after metamorphism. 6, the main mechanism causing bacterial resistance is due to the production of bacteria (inactivated enzymes) or (inactivation enzymes). 7 、 amide local anesthetic is a series of local anesthetics which are replaced by (amide bond) (benzoic acid ester local anesthetic) (ester key). 8 、 skeletal muscle relaxant can be used as auxiliary drug for general anesthetics, because these drugs contain quaternary ammonium salt structure in chemical structure, can reduce the dosage of general anesthetics and reduce the occurrence of adverse reactions. 9, the effect and speed of barbiturates are related to the drug itself (dissociation constant) and (lipid solubility), while the duration of action is related to the metabolism of (5, 5- double substituent). A molecular phenobarbital (amide structure), the sodium salt solution at room temperature for not stable, easy to be hydrolyzed (phenyl butyryl urea) lose activity, Phenobarbital Sodium for Injection for injection. 10, Aspirin in the acidic impurities is (Shui Yangsuan), the identification method for adding (FeCl3 color reaction occurs). In 11, the antibacterial mechanism of azole antifungal drugs: at low concentrations inhibit