anterior cervical discectomy with arthroplasty versus arthrodesis for single-level cervical spondylosis a systematic review and meta-analysis颈椎前路椎间盘切除术和关节成形术和关节固定术单层颈椎病系统回顾和荟萃分析.pdfVIP

Anterior Cervical Discectomy with Arthroplasty versus Arthrodesis for Single-Level Cervical Spondylosis: A Systematic Review and Meta-Analysis 1,2 2,3 2 1,4 1 2,5 Aria Fallah *, Elie A. Akl , Shanil Ebrahim , George M. Ibrahim , Alireza Mansouri , Clary J. Foote , Yuqing Zhang2,6, Michael G. Fehlings 1,7,8 1 Division of Neurosurgery, University of Toronto, Toronto, Canada, 2 Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada, 3 Department of Medicine, State University of New York at Buffalo, Buffalo, New York, United States of America, 4 Institute of Medical Sciences, University of Toronto, Toronto, Canada, 5 Division of Orthopedic Surgery, McMaster University, Hamilton, Canada, 6 Guang’anmen Hospital, China Academy of Chinese Medical Science, Beijing, China, 7 Toronto Western Research Institute, Toronto Western Hospital, Toronto, Canada, 8 Krembil Neuroscience Center, University Health Network, Toronto, Canada Abstract Objective: To estimate the effectiveness of anterior cervical discectomy with arthroplasty (ACDA) compared to anterior cervical discectomy with fusion (ACDF) for patient-important outcomes for single-level cervical spondylosis. Data sources: Electronic databases (MEDLINE, EMBASE, Cochrane Register for Randomized Controlled Trials, BIOSIS and LILACS), archives of spine meetings and bibliographies of relevant articles. Study selection: We included RCTs of ACDF versus ACDA in adult patients with single-level cervical spondylosis reporting at least one of the following outcomes: functionality, neurological success, neck pain, arm pain, quality of life, surgery for adjacent level degeneration (ALD),