comparing proteomics and risc immunoprecipitations to identify targets of epstein-barr viral mirnas比较蛋白质组学和risc免疫沉淀反应来确定巴尔病毒microrna的目标.pdfVIP

Comparing Proteomics and RISC Immunoprecipitations to Identify Targets of Epstein-Barr Viral miRNAs Malika Kuzembayeva, Ya-Fang Chiu, Bill Sugden* McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America Abstract Epstein-Barr virus is a gamma-herpes virus that is causally associated with several lymphomas and carcinomas. This virus encodes at least 25 pre-miRNAs, which are expressed in infected cells to yield more than 50 detected mature miRNAs. miRNAs are small, non-coding RNAs th