comparison between eq-5d and sf-6d utility in rural residents of jiangsu province, china比较eq-5d和sf-6d效用在江苏省农村居民,中国.pdfVIP

Comparison between EQ-5D and SF-6D Utility in Rural Residents of Jiangsu Province, China 1,2 1,2 1,2 3 1 3 1,2 Hui Jin , Bei Wang , Qian Gao , Jianqian Chao , Siyuan Wang , Lin Tian , Pei Liu * 1 Department of Epidemiology and Health Statistics, Southeast University, Nanjing, China, 2 Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China, 3 Department of Medical Insurance, Southeast University, Nanjing, China Abstract Background: The SF-6D and EQ-5D are widely used generic index measures as health-related quality of life. We assessed within-subject agreement between SF-6D and EQ-5D utilities with different preference weights, and their validities in measuring Chinese rural residents, before and after standardization scores. Methodology/Principal Findings: Rural residents over 18 years old were interviewed using EQ-5D and SF-6D in Jiangsu Province, China. EQ-5D utility-scoring algorithms were used from three conversion tables from the United Kingdom, Japan, and the United States. Validities, Sensitivity and agreement between instruments were computed and compared. Factors affecting utility difference were explored with multiple liner regression models. Scores with standardization intervals of 0–1 in the two instruments were analyzed by the use of the above methods again. In 929 respondents, relative efficiency statistic and receiver operating characteristic curves analysis showed SF-6D to be the more efficient, followed by the EQ-5D model in Japan weights. Bland–Altman plot analysis showed paired SF-6D/EQ-5D in UK weights had better agreement. Though some risk factors were found, multi