deficiency of flcn in mouse kidney led to development of polycystic kidneys and renal neoplasia老鼠肾脏flcn不足导致多囊肾和肾肿瘤的发展.pdfVIP

Deficiency of FLCN in Mouse Kidney Led to Development of Polycystic Kidneys and Renal Neoplasia 1 1,2 1 3 4 5 1 Jindong Chen *, Kunihiko Futami , David Petillo , Jun Peng , Pengfei Wang , Jared Knol , Yan Li , Sok- 1,6 1 1,7 8 9 1 8 Kean Khoo , Dan Huang , Chao-Nan Qian , Ping Zhao , Karl Dykyma , Racheal Zhang , Brian Cao , 10 9 5 1,11 Ximing J. Yang , Kyle Furge , Bart O. Williams , Bin Tean Teh * 1 Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, Michigan, United States of America, 2 Course of Applied Marine Biosciences, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan, Minato-ku, Tokyo, Japan, 3 Genomic Medicine Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, 4 Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, 5 Laboratory of Cell Signaling and Cancinogenesis, Van Andel Research Institute, Grand Rapids, Michigan, United States of America, 6 Laboratory of Germline Modification and Cytogenetics, Van Andel Research Institute, Grand Rapids, Michigan, United States of America, 7 Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China, 8 Laboratory of Antibody Technology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America, 9 Laboratory of Computational Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America, 10 Surgical Pathology, Nort